| http://purl.uniprot.org/citations/19692572 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19692572 | http://www.w3.org/2000/01/rdf-schema#comment | "The small ubiquitin-like modifier SUMO conjugates transcription factors and suppresses their respective activation of target genes. Although various SUMO-modified transcription factors have been isolated, mechanisms whereby sumoylated-substrates modulate transcription remain unknown. Here, we purified ARIP4 (AR interacting protein 4, a Rad54 family member and a SNF2 chromatin remodeling factor), which interacts with sumoylated Ad4BP/SF-1 through two SUMO-interacting motifs and one Ad4BP/SF-1-binding region. Remarkably, ARIP4 also interacts selectively with other sumoylated nuclear receptors including LRH-1, AR, and GR. Interestingly, the ATPase activity of ARIP4 was stimulated in the presence of sumoylated Ad4BP/SF-1 and the Ad4BP/SF-1-binding site containing double-stranded DNA. ChIP assays and siRNA studies strongly suggested that ARIP4 temporally suppresses Ad4BP/SF-1-mediated transcription through its transient recruitment to target genes. These findings suggest that ARIP4 may be a cofactor that modulates SUMO-mediated fine-tuning of transcriptional suppression."xsd:string |
| http://purl.uniprot.org/citations/19692572 | http://purl.org/dc/terms/identifier | "doi:10.1091/mbc.e08-12-1247"xsd:string |
| http://purl.uniprot.org/citations/19692572 | http://purl.uniprot.org/core/author | "Komatsu T."xsd:string |
| http://purl.uniprot.org/citations/19692572 | http://purl.uniprot.org/core/author | "Ogawa H."xsd:string |
| http://purl.uniprot.org/citations/19692572 | http://purl.uniprot.org/core/author | "Hiraoka Y."xsd:string |
| http://purl.uniprot.org/citations/19692572 | http://purl.uniprot.org/core/author | "Morohashi K."xsd:string |
| http://purl.uniprot.org/citations/19692572 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19692572 | http://purl.uniprot.org/core/name | "Mol Biol Cell"xsd:string |
| http://purl.uniprot.org/citations/19692572 | http://purl.uniprot.org/core/pages | "4235-4245"xsd:string |
| http://purl.uniprot.org/citations/19692572 | http://purl.uniprot.org/core/title | "Transcriptional Suppression by Transient Recruitment of ARIP4 to Sumoylated nuclear receptor Ad4BP/SF-1."xsd:string |
| http://purl.uniprot.org/citations/19692572 | http://purl.uniprot.org/core/volume | "20"xsd:string |
| http://purl.uniprot.org/citations/19692572 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/19692572 |
| http://purl.uniprot.org/citations/19692572 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/19692572 |
| http://purl.uniprot.org/uniprot/#_A0A1E1GJF0-mappedCitation-19692572 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19692572 |
| http://purl.uniprot.org/uniprot/#_B3KN64-mappedCitation-19692572 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19692572 |
| http://purl.uniprot.org/uniprot/#_B3KV54-mappedCitation-19692572 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19692572 |
| http://purl.uniprot.org/uniprot/#_B4E3V6-mappedCitation-19692572 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19692572 |
| http://purl.uniprot.org/uniprot/#_B6ZGU8-mappedCitation-19692572 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19692572 |
| http://purl.uniprot.org/uniprot/#_F1DAM0-mappedCitation-19692572 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19692572 |
| http://purl.uniprot.org/uniprot/#_F1D8R8-mappedCitation-19692572 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19692572 |
| http://purl.uniprot.org/uniprot/#_O75925-mappedCitation-19692572 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19692572 |
| http://purl.uniprot.org/uniprot/#_O75928-mappedCitation-19692572 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19692572 |
| http://purl.uniprot.org/uniprot/#_Q13285-mappedCitation-19692572 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19692572 |
| http://purl.uniprot.org/uniprot/#_L8ECB8-mappedCitation-19692572 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19692572 |