http://purl.uniprot.org/citations/19693710 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/19693710 | http://www.w3.org/2000/01/rdf-schema#comment | "Wild-type and alpha5 null mutant mice were used to identify nicotinic cholinergic receptors (nAChRs) that mediate alpha-conotoxin MII (alpha-CtxMII)-resistant dopamine (DA) release from striatal synaptosomes. Concentration-effect curves for ACh-stimulated release (20 s) were monophasic when wild-type synaptosomes were assayed but biphasic with synaptosomes from the alpha5 null mutant. Deleting the alpha5 gene also resulted in decreased maximal ACh-stimulated alpha-CtxMII-resistant DA release. When a shorter perfusion time (5 s) was used, biphasic curves were detected in both wild-type and alpha5 null mutants, indicative of high- and low-sensitivity (HS and LS) activity. In addition, DHbetaE-sensitive (HS) and DHbetaE-resistant (LS) components were found in both genotypes. These results indicate that alpha-CtxMII-resistant DA release is mediated by alpha4alpha5beta2, (alpha4)(2)(beta2)(3) (HS), and (alpha4)(3)(beta2)(2) (LS) nAChRs."xsd:string |
http://purl.uniprot.org/citations/19693710 | http://purl.org/dc/terms/identifier | "doi:10.1007/s12031-009-9263-y"xsd:string |
http://purl.uniprot.org/citations/19693710 | http://purl.uniprot.org/core/author | "Collins A.C."xsd:string |
http://purl.uniprot.org/citations/19693710 | http://purl.uniprot.org/core/author | "Marks M.J."xsd:string |
http://purl.uniprot.org/citations/19693710 | http://purl.uniprot.org/core/author | "McIntosh J.M."xsd:string |
http://purl.uniprot.org/citations/19693710 | http://purl.uniprot.org/core/author | "Salminen O."xsd:string |
http://purl.uniprot.org/citations/19693710 | http://purl.uniprot.org/core/author | "Grady S.R."xsd:string |
http://purl.uniprot.org/citations/19693710 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
http://purl.uniprot.org/citations/19693710 | http://purl.uniprot.org/core/name | "J Mol Neurosci"xsd:string |
http://purl.uniprot.org/citations/19693710 | http://purl.uniprot.org/core/pages | "91-95"xsd:string |
http://purl.uniprot.org/citations/19693710 | http://purl.uniprot.org/core/title | "Mouse striatal dopamine nerve terminals express alpha4alpha5beta2 and two stoichiometric forms of alpha4beta2*-nicotinic acetylcholine receptors."xsd:string |
http://purl.uniprot.org/citations/19693710 | http://purl.uniprot.org/core/volume | "40"xsd:string |
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