http://purl.uniprot.org/citations/19710009 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/19710009 | http://www.w3.org/2000/01/rdf-schema#comment | "Growth-blocking peptide (GBP) is a hormone-like peptide that suppresses the growth of the host armyworm. Although the 23-amino acid GBP (1-23 GBP) is expressed in nonparasitized armyworm plasma, the parasitization by wasp produces the 28-amino acid GBP (1-28 GBP) through an elongation of the C-terminal amino acid sequence. In this study, we characterized the GBP variants, which consist of various lengths of the C-terminal region, by comparing their biological activities and three-dimensional structures. The results of an injection study indicate that 1-28 GBP most strongly suppresses larval growth. NMR analysis shows that these peptides have basically the same tertiary structures and that the extension of the C-terminal region is disordered. However, the C-terminal region of 1-28 GBP undergoes a conformational transition from a random coiled state to an alpha-helical state in the presence of dodecylphosphocholine micelles. This suggests that binding of the C-terminal region would affect larval growth activity."xsd:string |
http://purl.uniprot.org/citations/19710009 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m109.011148"xsd:string |
http://purl.uniprot.org/citations/19710009 | http://purl.uniprot.org/core/author | "Kawano K."xsd:string |
http://purl.uniprot.org/citations/19710009 | http://purl.uniprot.org/core/author | "Mizuguchi M."xsd:string |
http://purl.uniprot.org/citations/19710009 | http://purl.uniprot.org/core/author | "Yamamoto H."xsd:string |
http://purl.uniprot.org/citations/19710009 | http://purl.uniprot.org/core/author | "Kamiya M."xsd:string |
http://purl.uniprot.org/citations/19710009 | http://purl.uniprot.org/core/author | "Aizawa T."xsd:string |
http://purl.uniprot.org/citations/19710009 | http://purl.uniprot.org/core/author | "Umetsu Y."xsd:string |
http://purl.uniprot.org/citations/19710009 | http://purl.uniprot.org/core/author | "Hayakawa Y."xsd:string |
http://purl.uniprot.org/citations/19710009 | http://purl.uniprot.org/core/author | "Demura M."xsd:string |
http://purl.uniprot.org/citations/19710009 | http://purl.uniprot.org/core/author | "Kumaki Y."xsd:string |
http://purl.uniprot.org/citations/19710009 | http://purl.uniprot.org/core/author | "Muto K."xsd:string |
http://purl.uniprot.org/citations/19710009 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
http://purl.uniprot.org/citations/19710009 | http://purl.uniprot.org/core/name | "J Biol Chem"xsd:string |
http://purl.uniprot.org/citations/19710009 | http://purl.uniprot.org/core/pages | "29625-29634"xsd:string |
http://purl.uniprot.org/citations/19710009 | http://purl.uniprot.org/core/title | "C-terminal elongation of growth-blocking peptide enhances its biological activity and micelle binding affinity."xsd:string |
http://purl.uniprot.org/citations/19710009 | http://purl.uniprot.org/core/volume | "284"xsd:string |
http://purl.uniprot.org/citations/19710009 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/19710009 |
http://purl.uniprot.org/citations/19710009 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/19710009 |
http://purl.uniprot.org/uniprot/#_Q27913-mappedCitation-19710009 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19710009 |
http://purl.uniprot.org/uniprot/Q27913 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/19710009 |