| http://purl.uniprot.org/citations/19717423 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19717423 | http://www.w3.org/2000/01/rdf-schema#comment | "Antigen cross-presentation in dendritic cells is a complex intracellular membrane transport process, but the underlying molecular mechanisms remain to be thoroughly investigated. In this study, we examined the effect of siRNA-mediated knockdown of 57 Rab GTPases, the key regulators of membrane trafficking, on antigen cross-presentation. Twelve Rab GTPases were identified to be associated with antigen cross-presentation, and Rab3b/3c was indicated to be colocalized with MHC class I molecules at perinuclear tubular structure. Tracing with fluorescence protein-tagged beta(2)-microglobulin demonstrated that the MHC class I molecules were internalized from the plasma membrane to Rab3b/3c-positive compartments, which were also colocalized with the internalized transferrin. Moreover, depletion of Rab3b/3c strongly reduced the fast phase recycling rate of transferrin receptors. Furthermore, the Rab3b/3c-positive compartments were colocalized with a fraction of Rab27a at a juxtaposition of phagosomes. Together, these data demonstrate that Rab3b/3c-positive recycling vesicles are involved in and may constitute one of the recycling compartments in exogenous antigen cross-presentation."xsd:string |
| http://purl.uniprot.org/citations/19717423 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.0905684106"xsd:string |
| http://purl.uniprot.org/citations/19717423 | http://purl.uniprot.org/core/author | "Liu H."xsd:string |
| http://purl.uniprot.org/citations/19717423 | http://purl.uniprot.org/core/author | "Li L."xsd:string |
| http://purl.uniprot.org/citations/19717423 | http://purl.uniprot.org/core/author | "Liu T."xsd:string |
| http://purl.uniprot.org/citations/19717423 | http://purl.uniprot.org/core/author | "Li J."xsd:string |
| http://purl.uniprot.org/citations/19717423 | http://purl.uniprot.org/core/author | "Li N."xsd:string |
| http://purl.uniprot.org/citations/19717423 | http://purl.uniprot.org/core/author | "Liu N."xsd:string |
| http://purl.uniprot.org/citations/19717423 | http://purl.uniprot.org/core/author | "Wu Y."xsd:string |
| http://purl.uniprot.org/citations/19717423 | http://purl.uniprot.org/core/author | "Zhou J."xsd:string |
| http://purl.uniprot.org/citations/19717423 | http://purl.uniprot.org/core/author | "Zhang J."xsd:string |
| http://purl.uniprot.org/citations/19717423 | http://purl.uniprot.org/core/author | "Xie Z."xsd:string |
| http://purl.uniprot.org/citations/19717423 | http://purl.uniprot.org/core/author | "Wan Y."xsd:string |
| http://purl.uniprot.org/citations/19717423 | http://purl.uniprot.org/core/author | "Zou L."xsd:string |
| http://purl.uniprot.org/citations/19717423 | http://purl.uniprot.org/core/author | "Chai L."xsd:string |
| http://purl.uniprot.org/citations/19717423 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19717423 | http://purl.uniprot.org/core/name | "Proc Natl Acad Sci U S A"xsd:string |
| http://purl.uniprot.org/citations/19717423 | http://purl.uniprot.org/core/pages | "15801-15806"xsd:string |
| http://purl.uniprot.org/citations/19717423 | http://purl.uniprot.org/core/title | "The GTPase Rab3b/3c-positive recycling vesicles are involved in cross-presentation in dendritic cells."xsd:string |
| http://purl.uniprot.org/citations/19717423 | http://purl.uniprot.org/core/volume | "106"xsd:string |
| http://purl.uniprot.org/citations/19717423 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/19717423 |
| http://purl.uniprot.org/citations/19717423 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/19717423 |
| http://purl.uniprot.org/uniprot/P61026#attribution-9CEC6B797CBCF69F2BEB90CB902207E9 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/19717423 |
| http://purl.uniprot.org/uniprot/P61020#attribution-9CEC6B797CBCF69F2BEB90CB902207E9 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/19717423 |