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http://purl.uniprot.org/citations/19732400 | http://www.w3.org/2000/01/rdf-schema#comment | "Stonins are a small family of evolutionarily conserved clathrin adaptor complex AP-2mu-related factors that may act as cargo-specific sorting adaptors in endocytosis and perhaps beyond. Whereas little is known about the localization and function of stonin 1, recent work suggests that stonin 2 serves as a linker between the endocytic proteins AP-2 and Eps15 and the calcium-sensing synaptic vesicle (SV) protein synaptotagmin 1. The molecular determinants involved in the recognition of SV cargo by the mu-homology domain of stonin 2 are evolutionarily conserved from worm to man, thereby identifying stonin 2 and its invertebrate homologs uncoordinated (UNC)-41 and stoned B as endocytic adaptors dedicated to the retrieval of surface-stranded SV proteins, most notably synaptotagmin. In this review, we summarize the current state of knowledge about mammalian stonins with a special focus on the role of stonin 2 in SV recycling at presynaptic nerve terminals."xsd:string |
http://purl.uniprot.org/citations/19732400 | http://purl.org/dc/terms/identifier | "doi:10.1111/j.1600-0854.2009.00971.x"xsd:string |
http://purl.uniprot.org/citations/19732400 | http://purl.uniprot.org/core/author | "Haucke V."xsd:string |
http://purl.uniprot.org/citations/19732400 | http://purl.uniprot.org/core/author | "Maritzen T."xsd:string |
http://purl.uniprot.org/citations/19732400 | http://purl.uniprot.org/core/author | "Podufall J."xsd:string |
http://purl.uniprot.org/citations/19732400 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
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http://purl.uniprot.org/citations/19732400 | http://purl.uniprot.org/core/pages | "8-15"xsd:string |
http://purl.uniprot.org/citations/19732400 | http://purl.uniprot.org/core/title | "Stonins--specialized adaptors for synaptic vesicle recycling and beyond?"xsd:string |
http://purl.uniprot.org/citations/19732400 | http://purl.uniprot.org/core/volume | "11"xsd:string |
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