http://purl.uniprot.org/citations/19733917 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/19733917 | http://www.w3.org/2000/01/rdf-schema#comment | "Epitope reactivity of multiple sclerosis (MS) plasma antibodies against the Epstein-Barr virus protein EBNA-1 and its association with HLA DRB1*1501 status was investigated in a case-referent study. Based on EBNA-1 fragment reactivity and the effect of peptide blocking, four 29-36 amino acid long EBNA-1 fragments were selected for detailed studies. MS cases had increased antibody reactivity against several EBNA-1 domains, of which antibodies against EBNA-1 (amino acid 385-420) in HLA DRB1*1501 positive individuals were associated with a 24-fold risk increase for MS. The data need confirmation in a larger sample but suggest a role for this epitope in the autoimmune pathogenesis of MS."xsd:string |
http://purl.uniprot.org/citations/19733917 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.jneuroim.2009.08.004"xsd:string |
http://purl.uniprot.org/citations/19733917 | http://purl.uniprot.org/core/author | "Sundstrom P."xsd:string |
http://purl.uniprot.org/citations/19733917 | http://purl.uniprot.org/core/author | "Lundgren E."xsd:string |
http://purl.uniprot.org/citations/19733917 | http://purl.uniprot.org/core/author | "Nystrom M."xsd:string |
http://purl.uniprot.org/citations/19733917 | http://purl.uniprot.org/core/author | "Ruuth K."xsd:string |
http://purl.uniprot.org/citations/19733917 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
http://purl.uniprot.org/citations/19733917 | http://purl.uniprot.org/core/name | "J Neuroimmunol"xsd:string |
http://purl.uniprot.org/citations/19733917 | http://purl.uniprot.org/core/pages | "102-107"xsd:string |
http://purl.uniprot.org/citations/19733917 | http://purl.uniprot.org/core/title | "Antibodies to specific EBNA-1 domains and HLA DRB1*1501 interact as risk factors for multiple sclerosis."xsd:string |
http://purl.uniprot.org/citations/19733917 | http://purl.uniprot.org/core/volume | "215"xsd:string |
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