| http://purl.uniprot.org/citations/19734539 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19734539 | http://www.w3.org/2000/01/rdf-schema#comment | "8-Oxo-2'-deoxyguanosine (8-oxodG) is one of the most important oxidative DNA lesions, and G-rich telomeric DNA is especially susceptible to oxidative DNA damage. RecQ helicases WRN and BLM and telomere-binding protein POT1 are thought to play roles in telomere maintenance. This study examines the ability of WRN, BLM, and RecQ5 to unwind and POT1 to bind telomeric D-loops containing 8-oxodG. The results demonstrate that WRN and BLM preferentially unwind telomeric D-loops containing 8-oxodG and that POT1 binds with higher affinity to telomeric D-loops with 8-oxodG but shows no preference for telomeric single-stranded DNA with 8-oxodG. We speculate that telomeric D-loops with 8-oxodG may have a greater tendency to form G-quadruplex DNA structures than telomeric DNA lacking 8-oxodG."xsd:string |
| http://purl.uniprot.org/citations/19734539 | http://purl.org/dc/terms/identifier | "doi:10.1074/jbc.m109.027532"xsd:string |
| http://purl.uniprot.org/citations/19734539 | http://purl.uniprot.org/core/author | "Ghosh A."xsd:string |
| http://purl.uniprot.org/citations/19734539 | http://purl.uniprot.org/core/author | "Bohr V.A."xsd:string |
| http://purl.uniprot.org/citations/19734539 | http://purl.uniprot.org/core/author | "Rossi M.L."xsd:string |
| http://purl.uniprot.org/citations/19734539 | http://purl.uniprot.org/core/author | "Aulds J."xsd:string |
| http://purl.uniprot.org/citations/19734539 | http://purl.uniprot.org/core/author | "Croteau D."xsd:string |
| http://purl.uniprot.org/citations/19734539 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19734539 | http://purl.uniprot.org/core/name | "J Biol Chem"xsd:string |
| http://purl.uniprot.org/citations/19734539 | http://purl.uniprot.org/core/pages | "31074-31084"xsd:string |
| http://purl.uniprot.org/citations/19734539 | http://purl.uniprot.org/core/title | "Telomeric D-loops containing 8-oxo-2'-deoxyguanosine are preferred substrates for Werner and Bloom syndrome helicases and are bound by POT1."xsd:string |
| http://purl.uniprot.org/citations/19734539 | http://purl.uniprot.org/core/volume | "284"xsd:string |
| http://purl.uniprot.org/citations/19734539 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/19734539 |
| http://purl.uniprot.org/citations/19734539 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/19734539 |
| http://purl.uniprot.org/uniprot/P54132#attribution-418244E5DC7A388DD34F5EEE4CA21C36 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/19734539 |
| http://purl.uniprot.org/uniprot/Q9NUX5#attribution-418244E5DC7A388DD34F5EEE4CA21C36 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/19734539 |
| http://purl.uniprot.org/uniprot/Q14191#attribution-418244E5DC7A388DD34F5EEE4CA21C36 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/19734539 |
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| http://purl.uniprot.org/uniprot/#_Q14191-mappedCitation-19734539 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19734539 |
| http://purl.uniprot.org/uniprot/#_B7Z7M5-mappedCitation-19734539 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19734539 |
| http://purl.uniprot.org/uniprot/#_A8MTK3-mappedCitation-19734539 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19734539 |
| http://purl.uniprot.org/uniprot/#_B2RAN0-mappedCitation-19734539 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19734539 |
| http://purl.uniprot.org/uniprot/#_B7Z8C1-mappedCitation-19734539 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19734539 |
| http://purl.uniprot.org/uniprot/#_B7ZKN7-mappedCitation-19734539 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19734539 |