| http://purl.uniprot.org/citations/19737519 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19737519 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19737519 | http://www.w3.org/2000/01/rdf-schema#comment | "The dynein-related AAA ATPase Rea1 is a preribosomal factor that triggers an unknown maturation step in 60S subunit biogenesis. Using electron microscopy, we show that Rea1's motor domain is docked to the pre-60S particle and its tail-like structure, harboring a metal ion-dependent adhesion site (MIDAS), protrudes from the preribosome. Typically, integrins utilize a MIDAS to bind extracellular ligands, an interaction that is strengthened under applied tensile force. Likewise, the Rea1 MIDAS binds the preribosomal factor Rsa4, which is located on the pre-60S subunit at a site that is contacted by the flexible Rea1 tail. The MIDAS-Rsa4 interaction is essential for ATP-dependent dissociation of a group of non-ribosomal factors from the pre-60S particle. Thus, Rea1 aligns with its interacting partners on the preribosome to effect a necessary step on the path to the export-competent 60S subunit."xsd:string |
| http://purl.uniprot.org/citations/19737519 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.cell.2009.06.045"xsd:string |
| http://purl.uniprot.org/citations/19737519 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.cell.2009.06.045"xsd:string |
| http://purl.uniprot.org/citations/19737519 | http://purl.uniprot.org/core/author | "Hurt E."xsd:string |
| http://purl.uniprot.org/citations/19737519 | http://purl.uniprot.org/core/author | "Hurt E."xsd:string |
| http://purl.uniprot.org/citations/19737519 | http://purl.uniprot.org/core/author | "Bottcher B."xsd:string |
| http://purl.uniprot.org/citations/19737519 | http://purl.uniprot.org/core/author | "Bottcher B."xsd:string |
| http://purl.uniprot.org/citations/19737519 | http://purl.uniprot.org/core/author | "Pertschy B."xsd:string |
| http://purl.uniprot.org/citations/19737519 | http://purl.uniprot.org/core/author | "Pertschy B."xsd:string |
| http://purl.uniprot.org/citations/19737519 | http://purl.uniprot.org/core/author | "Kressler D."xsd:string |
| http://purl.uniprot.org/citations/19737519 | http://purl.uniprot.org/core/author | "Kressler D."xsd:string |
| http://purl.uniprot.org/citations/19737519 | http://purl.uniprot.org/core/author | "Galani K."xsd:string |
| http://purl.uniprot.org/citations/19737519 | http://purl.uniprot.org/core/author | "Galani K."xsd:string |
| http://purl.uniprot.org/citations/19737519 | http://purl.uniprot.org/core/author | "Bassler J."xsd:string |
| http://purl.uniprot.org/citations/19737519 | http://purl.uniprot.org/core/author | "Bassler J."xsd:string |
| http://purl.uniprot.org/citations/19737519 | http://purl.uniprot.org/core/author | "Diepholz M."xsd:string |
| http://purl.uniprot.org/citations/19737519 | http://purl.uniprot.org/core/author | "Diepholz M."xsd:string |
| http://purl.uniprot.org/citations/19737519 | http://purl.uniprot.org/core/author | "Ulbrich C."xsd:string |
| http://purl.uniprot.org/citations/19737519 | http://purl.uniprot.org/core/author | "Ulbrich C."xsd:string |
| http://purl.uniprot.org/citations/19737519 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19737519 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19737519 | http://purl.uniprot.org/core/name | "Cell"xsd:string |
| http://purl.uniprot.org/citations/19737519 | http://purl.uniprot.org/core/name | "Cell"xsd:string |