| http://purl.uniprot.org/citations/19758564 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19758564 | http://www.w3.org/2000/01/rdf-schema#comment | "The yeast Dsl1p vesicle tethering complex, comprising the three subunits Dsl1p, Dsl3p, and Tip20p, is stably associated with three endoplasmic reticulum-localized Q-SNAREs and is believed to play a central role in the tethering and fusion of Golgi-derived COP-I transport vesicles. Dsl1p also interacts directly with COP-I subunits. We now show that binding of Dsl1p to COP-I subunits involves binding sites identical to those involved in interactions between COP-I subunits that stabilize the COP-I coat. Cells with defects in Dsl/SNARE complex function show massive accumulation of COP-I-coated vesicles in a cluster to which COP-II coat proteins are also recruited. Our results suggest that binding of Dsl/SNARE complex to the COP-I coat complex serves two functions: to mediate vesicle tethering and to assist the uncoating process by blocking domains in COP-I that drive repolymerization and the formation of large COP-I aggregates."xsd:string |
| http://purl.uniprot.org/citations/19758564 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.devcel.2009.07.012"xsd:string |
| http://purl.uniprot.org/citations/19758564 | http://purl.uniprot.org/core/author | "Schmitt H.D."xsd:string |
| http://purl.uniprot.org/citations/19758564 | http://purl.uniprot.org/core/author | "Wurm C.A."xsd:string |
| http://purl.uniprot.org/citations/19758564 | http://purl.uniprot.org/core/author | "Wenzel D."xsd:string |
| http://purl.uniprot.org/citations/19758564 | http://purl.uniprot.org/core/author | "Zink S."xsd:string |
| http://purl.uniprot.org/citations/19758564 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19758564 | http://purl.uniprot.org/core/name | "Dev Cell"xsd:string |
| http://purl.uniprot.org/citations/19758564 | http://purl.uniprot.org/core/pages | "403-416"xsd:string |
| http://purl.uniprot.org/citations/19758564 | http://purl.uniprot.org/core/title | "A link between ER tethering and COP-I vesicle uncoating."xsd:string |
| http://purl.uniprot.org/citations/19758564 | http://purl.uniprot.org/core/volume | "17"xsd:string |
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| http://purl.uniprot.org/uniprot/#_A6NNZ2-mappedCitation-19758564 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19758564 |
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