| http://purl.uniprot.org/citations/19763914 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19763914 | http://www.w3.org/2000/01/rdf-schema#comment | "Different p120ctn isoforms exert different, even opposing, effects on tumor cell growth depending on the level of E-cadherin expression, but the impact on clinicopathological parameters of lung cancer patients is not clear. Herein, we investigate the correlation between pan-p120ctn, p120ctn isoform 1, and E-cadherin expression and clinicopathological parameters, especially prognosis, of lung cancer patients. Immunohistochemistry on 20 specimens of normal bronchial epthelium revealed that, p120ctn isoform 1 was not expressed at the membrane; only weak cytoplasmic expression was seen. In contrast, both pan-p120ctn and E-cadherin were expressed clearly on the cell membrane or in the cytoplasmic peri-membrane region. However, in squamous cell lung cancer or lung adenocarcinomas, p120ctn isoform 1 over-expressed in the cytoplasm accompany with the abnormal pan-p120ctn and E-cadherin cytoplasm expression. p120ctn isoform 1 over-expression correlated positively with lymph node metastasis, poor differentiation, histological type, and high TNM stage. Cytoplasmic p120ctn isoform 1 expression in metastatic nodules was always higher than in the primary tumor. While the mean survival times of patients with normal p120 ctn isoform 1 or pan-p120ctn expression differed significantly, the mean survival times of patients with abnormal expression were similar. Lymph node metastasis, TNM stage, abnormal pan-p120ctn expression, and p120ctn isoform 1 over-expression were all independent factors affecting the prognosis of lung cancer patients. Over-expression of p120ctn isoform 1 positively correlated with poor prognosis of lung cancer patients, and therefore may be a useful marker of lung cancer patient survival."xsd:string |
| http://purl.uniprot.org/citations/19763914 | http://purl.org/dc/terms/identifier | "doi:10.1007/s12032-009-9300-2"xsd:string |
| http://purl.uniprot.org/citations/19763914 | http://purl.uniprot.org/core/author | "Liu Y."xsd:string |
| http://purl.uniprot.org/citations/19763914 | http://purl.uniprot.org/core/author | "Liu N."xsd:string |
| http://purl.uniprot.org/citations/19763914 | http://purl.uniprot.org/core/author | "Zhang Y."xsd:string |
| http://purl.uniprot.org/citations/19763914 | http://purl.uniprot.org/core/author | "Miao Y."xsd:string |
| http://purl.uniprot.org/citations/19763914 | http://purl.uniprot.org/core/author | "Yu J.H."xsd:string |
| http://purl.uniprot.org/citations/19763914 | http://purl.uniprot.org/core/author | "Wang E.H."xsd:string |
| http://purl.uniprot.org/citations/19763914 | http://purl.uniprot.org/core/author | "Xu H.T."xsd:string |
| http://purl.uniprot.org/citations/19763914 | http://purl.uniprot.org/core/author | "Dai S.D."xsd:string |
| http://purl.uniprot.org/citations/19763914 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
| http://purl.uniprot.org/citations/19763914 | http://purl.uniprot.org/core/name | "Med Oncol"xsd:string |
| http://purl.uniprot.org/citations/19763914 | http://purl.uniprot.org/core/pages | "880-886"xsd:string |
| http://purl.uniprot.org/citations/19763914 | http://purl.uniprot.org/core/title | "p120ctn isoform 1 expression significantly correlates with abnormal expression of E-cadherin and poor survival of lung cancer patients."xsd:string |
| http://purl.uniprot.org/citations/19763914 | http://purl.uniprot.org/core/volume | "27"xsd:string |
| http://purl.uniprot.org/citations/19763914 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/19763914 |
| http://purl.uniprot.org/citations/19763914 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/19763914 |
| http://purl.uniprot.org/uniprot/#_A0A0E3XJU3-mappedCitation-19763914 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19763914 |
| http://purl.uniprot.org/uniprot/#_A0A0U2ZQU7-mappedCitation-19763914 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19763914 |
| http://purl.uniprot.org/uniprot/#_A0A140HMB1-mappedCitation-19763914 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19763914 |
| http://purl.uniprot.org/uniprot/#_A0A3G2JNR5-mappedCitation-19763914 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19763914 |
| http://purl.uniprot.org/uniprot/#_A0A6C0N5X1-mappedCitation-19763914 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19763914 |
| http://purl.uniprot.org/uniprot/#_A5D8W4-mappedCitation-19763914 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19763914 |
| http://purl.uniprot.org/uniprot/#_B3GN61-mappedCitation-19763914 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19763914 |