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http://purl.uniprot.org/citations/19764566http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/19764566http://www.w3.org/2000/01/rdf-schema#comment"

Objective

To investigate the expressions of HSP60, TLR4 and NF-kappaBp65 in the peripheral blood of patients with atopic dermatitis (AD) and their roles in the pathogenesis of AD.

Methods

RT-PCR, immunocytochemistry and ELISA were performed to measure the mRNA expressions of TLR4 and NF-kappaBp65 in the peripheral lymphocytes and monocytes, and the serum HSP60, respectively. A total of 17 patients with AD were recruited for the study, with 15 healthy people serving as controls.

Results

The levels of HSP60, TLR4 mRNA and NF-kappaBp65 were significantly higher in the peripheral blood of the patients with AD than in the controls (P<0.05).

Conclusion

HSP60, TLR4 and NF-kappaBp65 are overexpressed in the peripheral blood of patients with AD, which might be associated with the pathogenesis of AD."xsd:string
http://purl.uniprot.org/citations/19764566http://purl.uniprot.org/core/author"Gao Y."xsd:string
http://purl.uniprot.org/citations/19764566http://purl.uniprot.org/core/author"Guo Z.P."xsd:string
http://purl.uniprot.org/citations/19764566http://purl.uniprot.org/core/date"2009"xsd:gYear
http://purl.uniprot.org/citations/19764566http://purl.uniprot.org/core/name"Sichuan Da Xue Xue Bao Yi Xue Ban"xsd:string
http://purl.uniprot.org/citations/19764566http://purl.uniprot.org/core/pages"655-657"xsd:string
http://purl.uniprot.org/citations/19764566http://purl.uniprot.org/core/title"[Expression of HSP60, TLR4 and NF-kappaBp65 in the peripheral blood of patients with atopic dermatitis]."xsd:string
http://purl.uniprot.org/citations/19764566http://purl.uniprot.org/core/volume"40"xsd:string
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