http://purl.uniprot.org/citations/19780043 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/19780043 | http://www.w3.org/2000/01/rdf-schema#comment | "Our study investigates the dependence of response monitoring and error detection on genetic influences modulating the serotonergic system. This was done using the event-related potentials (ERPs) after error (Ne/ERN) and correct trials (Nc/CRN). To induce a sufficient amount of errors, a standard flanker task was used. The subjects (N = 94) were genotyped for the functional 5-HT1A C(-1019)G polymorphism. The results show that the 5-HT1A C(-1019)G polymorphism specifically modulates error detection. Neurophysiological modulations on error detection were paralleled by a similar modulation of response slowing after an error, reflecting the behavioral adaptation. The 5-HT1A -1019 CC genotype group showed a larger Ne and stronger posterror slowing than the CG and GG genotype groups. More general processes of performance monitoring, as reflected in the Nc/CRN, were not affected. The finding that error-specific processes, but not general response monitoring processes, are modulated by the 5-HT1A C(-1019)G polymorphism is underlined by a wavelet analysis. In summary, the results suggest a specific effect of the 5-HT1A C(-1019)G polymorphism on error monitoring, as reflected in the Ne, and suggest a neurobiological dissociation between processes of error monitoring and general response monitoring at the level of the serotonin 1A receptor system."xsd:string |
http://purl.uniprot.org/citations/19780043 | http://purl.org/dc/terms/identifier | "doi:10.1002/hbm.20892"xsd:string |
http://purl.uniprot.org/citations/19780043 | http://purl.uniprot.org/core/author | "Konrad C."xsd:string |
http://purl.uniprot.org/citations/19780043 | http://purl.uniprot.org/core/author | "Domschke K."xsd:string |
http://purl.uniprot.org/citations/19780043 | http://purl.uniprot.org/core/author | "Kolev V."xsd:string |
http://purl.uniprot.org/citations/19780043 | http://purl.uniprot.org/core/author | "Baffa A."xsd:string |
http://purl.uniprot.org/citations/19780043 | http://purl.uniprot.org/core/author | "Beste C."xsd:string |
http://purl.uniprot.org/citations/19780043 | http://purl.uniprot.org/core/author | "Falkenstein M."xsd:string |
http://purl.uniprot.org/citations/19780043 | http://purl.uniprot.org/core/author | "Yordanova J."xsd:string |
http://purl.uniprot.org/citations/19780043 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
http://purl.uniprot.org/citations/19780043 | http://purl.uniprot.org/core/name | "Hum Brain Mapp"xsd:string |
http://purl.uniprot.org/citations/19780043 | http://purl.uniprot.org/core/pages | "621-630"xsd:string |
http://purl.uniprot.org/citations/19780043 | http://purl.uniprot.org/core/title | "Functional 5-HT1a receptor polymorphism selectively modulates error-specific subprocesses of performance monitoring."xsd:string |
http://purl.uniprot.org/citations/19780043 | http://purl.uniprot.org/core/volume | "31"xsd:string |
http://purl.uniprot.org/citations/19780043 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/19780043 |
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