| http://purl.uniprot.org/citations/19780673 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19780673 | http://www.w3.org/2000/01/rdf-schema#comment | "Recently, we showed chronic hepatitis C to be associated with increased expression of HLA-E and identified peptide hepatitis C virus (HCV) core amino acids 35-44 as a ligand for HLA-E that stabilizes HLA-E expression, favoring inhibition of natural killer cell cytotoxicity. Here we describe HLA-E-restricted recognition of peptide HCV core amino acids 35-44 by CD8(+) T cells. Frequency of HLA-E-restricted responses was significantly higher in patients homozygous for the HLA-E(R) allele (60% vs 38%; P = .038). Moreover, we found that the HLA-E(R) allelic variant confers protection against chronic infection with HCV genotypes 2 and 3. Taken together, our data indicate an important immunomodulating function of HLA-E in hepatitis C."xsd:string |
| http://purl.uniprot.org/citations/19780673 | http://purl.org/dc/terms/identifier | "doi:10.1086/605889"xsd:string |
| http://purl.uniprot.org/citations/19780673 | http://purl.uniprot.org/core/author | "Vogel M."xsd:string |
| http://purl.uniprot.org/citations/19780673 | http://purl.uniprot.org/core/author | "Berg T."xsd:string |
| http://purl.uniprot.org/citations/19780673 | http://purl.uniprot.org/core/author | "Kramer B."xsd:string |
| http://purl.uniprot.org/citations/19780673 | http://purl.uniprot.org/core/author | "Korner C."xsd:string |
| http://purl.uniprot.org/citations/19780673 | http://purl.uniprot.org/core/author | "Schulte D."xsd:string |
| http://purl.uniprot.org/citations/19780673 | http://purl.uniprot.org/core/author | "Nattermann J."xsd:string |
| http://purl.uniprot.org/citations/19780673 | http://purl.uniprot.org/core/author | "Nischalke H.D."xsd:string |
| http://purl.uniprot.org/citations/19780673 | http://purl.uniprot.org/core/author | "Sauerbruch T."xsd:string |
| http://purl.uniprot.org/citations/19780673 | http://purl.uniprot.org/core/author | "Spengler U."xsd:string |
| http://purl.uniprot.org/citations/19780673 | http://purl.uniprot.org/core/author | "Steinberg V."xsd:string |
| http://purl.uniprot.org/citations/19780673 | http://purl.uniprot.org/core/author | "Rockstroh J.K."xsd:string |
| http://purl.uniprot.org/citations/19780673 | http://purl.uniprot.org/core/author | "Langhans B."xsd:string |
| http://purl.uniprot.org/citations/19780673 | http://purl.uniprot.org/core/author | "Michalk M."xsd:string |
| http://purl.uniprot.org/citations/19780673 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19780673 | http://purl.uniprot.org/core/name | "J Infect Dis"xsd:string |
| http://purl.uniprot.org/citations/19780673 | http://purl.uniprot.org/core/pages | "1397-1401"xsd:string |
| http://purl.uniprot.org/citations/19780673 | http://purl.uniprot.org/core/title | "The HLA-E(R)/HLA-E(R) genotype affects the natural course of hepatitis C virus (HCV) infection and is associated with HLA-E-restricted recognition of an HCV-derived peptide by interferon-gamma-secreting human CD8(+) T cells."xsd:string |
| http://purl.uniprot.org/citations/19780673 | http://purl.uniprot.org/core/volume | "200"xsd:string |
| http://purl.uniprot.org/citations/19780673 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/19780673 |
| http://purl.uniprot.org/citations/19780673 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/19780673 |
| http://purl.uniprot.org/uniprot/#_A0A0F7WBW2-mappedCitation-19780673 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19780673 |
| http://purl.uniprot.org/uniprot/#_A0A0A8LFF7-mappedCitation-19780673 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19780673 |