| http://purl.uniprot.org/citations/19805223 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19805223 | http://www.w3.org/2000/01/rdf-schema#comment | "The p53 target gene Wig-1 encodes a double-stranded-RNA-binding zinc finger protein. We show here that Wig-1 binds to p53 mRNA and stabilizes it through an AU-rich element (ARE) in the 3' UTR of the p53 mRNA. This effect is mirrored by enhanced p53 protein levels in both unstressed cells and cells exposed to p53-activating stress agents. Thus, the p53 target Wig-1 is a previously undescribed ARE-regulating protein that acts as a positive feedback regulator of p53, with implications both for the steady-state levels of p53 and for the p53 stress response. Our data reveal a previously undescribed link between the tumor suppressor p53 and posttranscriptional gene regulation via AREs in mRNA."xsd:string |
| http://purl.uniprot.org/citations/19805223 | http://purl.org/dc/terms/identifier | "doi:10.1073/pnas.0900862106"xsd:string |
| http://purl.uniprot.org/citations/19805223 | http://purl.uniprot.org/core/author | "Farnebo M."xsd:string |
| http://purl.uniprot.org/citations/19805223 | http://purl.uniprot.org/core/author | "Mahmoudi S."xsd:string |
| http://purl.uniprot.org/citations/19805223 | http://purl.uniprot.org/core/author | "Wiman K.G."xsd:string |
| http://purl.uniprot.org/citations/19805223 | http://purl.uniprot.org/core/author | "Norrild B."xsd:string |
| http://purl.uniprot.org/citations/19805223 | http://purl.uniprot.org/core/author | "Corcoran M."xsd:string |
| http://purl.uniprot.org/citations/19805223 | http://purl.uniprot.org/core/author | "Grander D."xsd:string |
| http://purl.uniprot.org/citations/19805223 | http://purl.uniprot.org/core/author | "Wilhelm M.T."xsd:string |
| http://purl.uniprot.org/citations/19805223 | http://purl.uniprot.org/core/author | "Rosenstierne M."xsd:string |
| http://purl.uniprot.org/citations/19805223 | http://purl.uniprot.org/core/author | "Glahder J.A."xsd:string |
| http://purl.uniprot.org/citations/19805223 | http://purl.uniprot.org/core/author | "Vilborg A."xsd:string |
| http://purl.uniprot.org/citations/19805223 | http://purl.uniprot.org/core/author | "Bersani C."xsd:string |
| http://purl.uniprot.org/citations/19805223 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19805223 | http://purl.uniprot.org/core/name | "Proc Natl Acad Sci U S A"xsd:string |
| http://purl.uniprot.org/citations/19805223 | http://purl.uniprot.org/core/pages | "15756-15761"xsd:string |
| http://purl.uniprot.org/citations/19805223 | http://purl.uniprot.org/core/title | "The p53 target Wig-1 regulates p53 mRNA stability through an AU-rich element."xsd:string |
| http://purl.uniprot.org/citations/19805223 | http://purl.uniprot.org/core/volume | "106"xsd:string |
| http://purl.uniprot.org/citations/19805223 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/19805223 |
| http://purl.uniprot.org/citations/19805223 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/19805223 |
| http://purl.uniprot.org/uniprot/#_A0A0A6YWE0-mappedCitation-19805223 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19805223 |
| http://purl.uniprot.org/uniprot/#_B9EI21-mappedCitation-19805223 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19805223 |
| http://purl.uniprot.org/uniprot/#_O54836-mappedCitation-19805223 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19805223 |
| http://purl.uniprot.org/uniprot/#_Q9HA38-mappedCitation-19805223 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19805223 |