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http://purl.uniprot.org/citations/19821846http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/19821846http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/19821846http://www.w3.org/2000/01/rdf-schema#comment"In the HLA-G locus, the 3'-untranslated region (3'-UTR) begins in the mid exon 6, and ends in exon 8. The occurrence of a 14-bp deletion within exon 8, the only mutation known until now in the 3'-UTR, has been considered a risk factor for disease and allograft rejection. To describe the polymorphism within this region, direct sequencing analysis was performed on 120 DNA samples from Portugal and Guinea-Bissau. Results indicate that exon 8 is less conserved than the coding exons. Nine single nucleotide polymorphisms and the previously described 14-bp deletion were found within exon 8 of both populations. Molecular diversity was higher in the Guinean samples than in the Portuguese; however, little differentiation was found among the populations, suggesting that local selection on exon 8 sequence variation is absent. The screening for sequence motifs suggests that polymorphism on this region may be involved in HLA-G post-transcriptional regulation and, therefore, in phenotype variation."xsd:string
http://purl.uniprot.org/citations/19821846http://purl.org/dc/terms/identifier"doi:10.1111/j.1744-313X.2009.00875.x"xsd:string
http://purl.uniprot.org/citations/19821846http://purl.org/dc/terms/identifier"doi:10.1111/j.1744-313x.2009.00875.x"xsd:string
http://purl.uniprot.org/citations/19821846http://purl.uniprot.org/core/author"Alvarez M."xsd:string
http://purl.uniprot.org/citations/19821846http://purl.uniprot.org/core/author"Alvarez M."xsd:string
http://purl.uniprot.org/citations/19821846http://purl.uniprot.org/core/author"Piedade J."xsd:string
http://purl.uniprot.org/citations/19821846http://purl.uniprot.org/core/author"Piedade J."xsd:string
http://purl.uniprot.org/citations/19821846http://purl.uniprot.org/core/author"Ribas G."xsd:string
http://purl.uniprot.org/citations/19821846http://purl.uniprot.org/core/author"Ribas G."xsd:string
http://purl.uniprot.org/citations/19821846http://purl.uniprot.org/core/author"Regateiro F."xsd:string
http://purl.uniprot.org/citations/19821846http://purl.uniprot.org/core/author"Regateiro F."xsd:string
http://purl.uniprot.org/citations/19821846http://purl.uniprot.org/core/author"Balseiro S."xsd:string
http://purl.uniprot.org/citations/19821846http://purl.uniprot.org/core/author"Balseiro S."xsd:string
http://purl.uniprot.org/citations/19821846http://purl.uniprot.org/core/date"2009"xsd:gYear
http://purl.uniprot.org/citations/19821846http://purl.uniprot.org/core/date"2009"xsd:gYear
http://purl.uniprot.org/citations/19821846http://purl.uniprot.org/core/name"Int. J. Immunogenet."xsd:string
http://purl.uniprot.org/citations/19821846http://purl.uniprot.org/core/name"Int J Immunogenet"xsd:string
http://purl.uniprot.org/citations/19821846http://purl.uniprot.org/core/pages"361-366"xsd:string
http://purl.uniprot.org/citations/19821846http://purl.uniprot.org/core/pages"361-366"xsd:string
http://purl.uniprot.org/citations/19821846http://purl.uniprot.org/core/title"HLA-G 3'-UTR SNP and 14-bp deletion polymorphisms in Portuguese and Guinea-Bissau populations."xsd:string
http://purl.uniprot.org/citations/19821846http://purl.uniprot.org/core/title"HLA-G 3'-UTR SNP and 14-bp deletion polymorphisms in Portuguese and Guinea-Bissau populations."xsd:string
http://purl.uniprot.org/citations/19821846http://purl.uniprot.org/core/volume"36"xsd:string
http://purl.uniprot.org/citations/19821846http://purl.uniprot.org/core/volume"36"xsd:string