| http://purl.uniprot.org/citations/19833919 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19833919 | http://www.w3.org/2000/01/rdf-schema#comment | "Elongation factor G (EF-G) is a guanosine triphosphatase (GTPase) that plays a crucial role in the translocation of transfer RNAs (tRNAs) and messenger RNA (mRNA) during translation by the ribosome. We report a crystal structure refined to 3.6 angstrom resolution of the ribosome trapped with EF-G in the posttranslocational state using the antibiotic fusidic acid. Fusidic acid traps EF-G in a conformation intermediate between the guanosine triphosphate and guanosine diphosphate forms. The interaction of EF-G with ribosomal elements implicated in stimulating catalysis, such as the L10-L12 stalk and the L11 region, and of domain IV of EF-G with the tRNA at the peptidyl-tRNA binding site (P site) and with mRNA shed light on the role of these elements in EF-G function. The stabilization of the mobile stalks of the ribosome also results in a more complete description of its structure."xsd:string |
| http://purl.uniprot.org/citations/19833919 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1179709"xsd:string |
| http://purl.uniprot.org/citations/19833919 | http://purl.uniprot.org/core/author | "Gao Y.G."xsd:string |
| http://purl.uniprot.org/citations/19833919 | http://purl.uniprot.org/core/author | "Selmer M."xsd:string |
| http://purl.uniprot.org/citations/19833919 | http://purl.uniprot.org/core/author | "Ramakrishnan V."xsd:string |
| http://purl.uniprot.org/citations/19833919 | http://purl.uniprot.org/core/author | "Kelley A.C."xsd:string |
| http://purl.uniprot.org/citations/19833919 | http://purl.uniprot.org/core/author | "Dunham C.M."xsd:string |
| http://purl.uniprot.org/citations/19833919 | http://purl.uniprot.org/core/author | "Weixlbaumer A."xsd:string |
| http://purl.uniprot.org/citations/19833919 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19833919 | http://purl.uniprot.org/core/name | "Science"xsd:string |
| http://purl.uniprot.org/citations/19833919 | http://purl.uniprot.org/core/pages | "694-699"xsd:string |
| http://purl.uniprot.org/citations/19833919 | http://purl.uniprot.org/core/title | "The structure of the ribosome with elongation factor G trapped in the posttranslocational state."xsd:string |
| http://purl.uniprot.org/citations/19833919 | http://purl.uniprot.org/core/volume | "326"xsd:string |
| http://purl.uniprot.org/citations/19833919 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/19833919 |
| http://purl.uniprot.org/citations/19833919 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/19833919 |
| http://purl.uniprot.org/uniprot/#_P35871-mappedCitation-19833919 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19833919 |
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| http://purl.uniprot.org/uniprot/#_P0DOY7-mappedCitation-19833919 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19833919 |
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| http://purl.uniprot.org/uniprot/#_P17291-mappedCitation-19833919 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19833919 |
| http://purl.uniprot.org/uniprot/#_P80339-mappedCitation-19833919 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19833919 |
| http://purl.uniprot.org/uniprot/#_P80340-mappedCitation-19833919 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19833919 |
| http://purl.uniprot.org/uniprot/#_P80371-mappedCitation-19833919 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19833919 |