| http://purl.uniprot.org/citations/19841671 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19841671 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19841671 | http://www.w3.org/2000/01/rdf-schema#comment | "UnlabelledParaplegin is an m-AAA protease of the mitochondrial inner membrane that is linked to hereditary spastic paraplegias. The gene encodes an FtsH-homology protease domain in tandem with an AAA+ homology ATPase domain. The protein is believed to form a hexamer that uses ATPase-driven conformational changes in its AAA-domain to deliver substrate peptides to its protease domain. We present the crystal structure of the AAA-domain of human paraplegin bound to ADP at 2.2 A. This enables assignment of the roles of specific side chains within the catalytic cycle, and provides the structural basis for understanding the mechanism of disease mutations.Enhanced versionThis article can also be viewed as an enhanced version in which the text of the article is integrated with interactive 3D representations and animated transitions. Please note that a web plugin is required to access this enhanced functionality. Instructions for the installation and use of the web plugin are available in Text S1."xsd:string |
| http://purl.uniprot.org/citations/19841671 | http://purl.org/dc/terms/identifier | "doi:10.1371/journal.pone.0006975"xsd:string |
| http://purl.uniprot.org/citations/19841671 | http://purl.org/dc/terms/identifier | "doi:10.1371/journal.pone.0006975"xsd:string |
| http://purl.uniprot.org/citations/19841671 | http://purl.uniprot.org/core/author | "Hammarstrom M."xsd:string |
| http://purl.uniprot.org/citations/19841671 | http://purl.uniprot.org/core/author | "Hammarstrom M."xsd:string |
| http://purl.uniprot.org/citations/19841671 | http://purl.uniprot.org/core/author | "Johansson I."xsd:string |
| http://purl.uniprot.org/citations/19841671 | http://purl.uniprot.org/core/author | "Johansson I."xsd:string |
| http://purl.uniprot.org/citations/19841671 | http://purl.uniprot.org/core/author | "Karlberg T."xsd:string |
| http://purl.uniprot.org/citations/19841671 | http://purl.uniprot.org/core/author | "Karlberg T."xsd:string |
| http://purl.uniprot.org/citations/19841671 | http://purl.uniprot.org/core/author | "Schuler H."xsd:string |
| http://purl.uniprot.org/citations/19841671 | http://purl.uniprot.org/core/author | "Schuler H."xsd:string |
| http://purl.uniprot.org/citations/19841671 | http://purl.uniprot.org/core/author | "van den Berg S."xsd:string |
| http://purl.uniprot.org/citations/19841671 | http://purl.uniprot.org/core/author | "van den Berg S."xsd:string |
| http://purl.uniprot.org/citations/19841671 | http://purl.uniprot.org/core/author | "Holmberg-Schiavone L."xsd:string |
| http://purl.uniprot.org/citations/19841671 | http://purl.uniprot.org/core/author | "Holmberg-Schiavone L."xsd:string |
| http://purl.uniprot.org/citations/19841671 | http://purl.uniprot.org/core/author | "Sagemark J."xsd:string |
| http://purl.uniprot.org/citations/19841671 | http://purl.uniprot.org/core/author | "Sagemark J."xsd:string |
| http://purl.uniprot.org/citations/19841671 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19841671 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19841671 | http://purl.uniprot.org/core/name | "PLoS ONE"xsd:string |
| http://purl.uniprot.org/citations/19841671 | http://purl.uniprot.org/core/name | "PLoS ONE"xsd:string |
| http://purl.uniprot.org/citations/19841671 | http://purl.uniprot.org/core/pages | "E6975"xsd:string |
| http://purl.uniprot.org/citations/19841671 | http://purl.uniprot.org/core/pages | "E6975"xsd:string |