| http://purl.uniprot.org/citations/19843951 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19843951 | http://www.w3.org/2000/01/rdf-schema#comment | "IL-17A and IL-17F regulate granulopoiesis and are produced by memory T cells. Rag1(-/-) recombinase-activating gene-deficient mice cannot produce mature T cells but maintain normal neutrophil counts. Athymic nude mice are neutropenic or have near-normal neutrophil counts, depending on the prevailing intestinal flora, and do not produce IL-17A. By contrast, thymi from Rag1(-/-) mice contain as much IL-17A as those from wild-type (WT) mice. IL-17A-producing cells are found in the double negative DN1 compartment of the Rag1(-/-) thymus and express intracellular CD3. These cells colonize the spleen and mesenteric lymph node and secrete IL-17A in vitro following stimulation with IL-23 at a level similar to that of WT splenocytes. Adoptively transferred Rag1(-/-) or WT thymocytes correct neutrophil counts in neutropenic nude mice. We conclude that the development of IL-17A-producing T-lineage cells requires an intact thymic epithelium, but not V(D)J recombination."xsd:string |
| http://purl.uniprot.org/citations/19843951 | http://purl.org/dc/terms/identifier | "doi:10.4049/jimmunol.0900887"xsd:string |
| http://purl.uniprot.org/citations/19843951 | http://purl.uniprot.org/core/author | "Smith E."xsd:string |
| http://purl.uniprot.org/citations/19843951 | http://purl.uniprot.org/core/author | "Sanders J.M."xsd:string |
| http://purl.uniprot.org/citations/19843951 | http://purl.uniprot.org/core/author | "Zarbock A."xsd:string |
| http://purl.uniprot.org/citations/19843951 | http://purl.uniprot.org/core/author | "von Vietinghoff S."xsd:string |
| http://purl.uniprot.org/citations/19843951 | http://purl.uniprot.org/core/author | "Ley K."xsd:string |
| http://purl.uniprot.org/citations/19843951 | http://purl.uniprot.org/core/author | "Bender T.P."xsd:string |
| http://purl.uniprot.org/citations/19843951 | http://purl.uniprot.org/core/author | "Stark M.A."xsd:string |
| http://purl.uniprot.org/citations/19843951 | http://purl.uniprot.org/core/author | "Rivera-Nieves J."xsd:string |
| http://purl.uniprot.org/citations/19843951 | http://purl.uniprot.org/core/author | "Duley A."xsd:string |
| http://purl.uniprot.org/citations/19843951 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19843951 | http://purl.uniprot.org/core/name | "J Immunol"xsd:string |
| http://purl.uniprot.org/citations/19843951 | http://purl.uniprot.org/core/pages | "5685-5693"xsd:string |
| http://purl.uniprot.org/citations/19843951 | http://purl.uniprot.org/core/title | "T-lineage cells require the thymus but not VDJ recombination to produce IL-17A and regulate granulopoiesis in vivo."xsd:string |
| http://purl.uniprot.org/citations/19843951 | http://purl.uniprot.org/core/volume | "183"xsd:string |
| http://purl.uniprot.org/citations/19843951 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/19843951 |
| http://purl.uniprot.org/citations/19843951 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/19843951 |
| http://purl.uniprot.org/uniprot/#_A0A087WPA7-mappedCitation-19843951 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19843951 |
| http://purl.uniprot.org/uniprot/#_D3YYP8-mappedCitation-19843951 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19843951 |
| http://purl.uniprot.org/uniprot/#_D3Z1S4-mappedCitation-19843951 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19843951 |
| http://purl.uniprot.org/uniprot/#_Q32MU3-mappedCitation-19843951 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19843951 |
| http://purl.uniprot.org/uniprot/#_Q62386-mappedCitation-19843951 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19843951 |
| http://purl.uniprot.org/uniprot/#_Q61421-mappedCitation-19843951 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19843951 |