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http://purl.uniprot.org/citations/19874820http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/19874820http://www.w3.org/2000/01/rdf-schema#comment"The abundant heterogeneous nuclear ribonucleoprotein M (hnRNP M) is able to associate with early spliceosomes and to influence splicing patterns of specific pre-mRNAs. Here, by a combination of immunoprecipitation and pull-down assays, we have identified PSF (polypyrimidine tract-binding protein-associated splicing factor) and p54(nrb), two highly related proteins involved in transcription and RNA processing, as new binding partners of hnRNP M. HnRNP M was found to co-localize with PSF within a subset of nuclear paraspeckles and to largely co-fractionate with PSF and p54(nrb) in biochemical nuclear matrix preparations. In cells transfected with an alternatively spliced preprotachykinin (PPT) minigene expression of hnRNP M promoted exon skipping while expression of PSF favours exon inclusion. The latter effect was reverted specifically by co-expressing the full length hnRNP M or a deletion mutant capable of interaction with PSF and p54(nrb). Together our data provide new insights and some functional implications on the hnRNP M network of interactions."xsd:string
http://purl.uniprot.org/citations/19874820http://purl.org/dc/terms/identifier"doi:10.1016/j.yexcr.2009.10.021"xsd:string
http://purl.uniprot.org/citations/19874820http://purl.uniprot.org/core/author"Marko M."xsd:string
http://purl.uniprot.org/citations/19874820http://purl.uniprot.org/core/author"Guialis A."xsd:string
http://purl.uniprot.org/citations/19874820http://purl.uniprot.org/core/author"Patrinou-Georgoula M."xsd:string
http://purl.uniprot.org/citations/19874820http://purl.uniprot.org/core/author"Leichter M."xsd:string
http://purl.uniprot.org/citations/19874820http://purl.uniprot.org/core/date"2010"xsd:gYear
http://purl.uniprot.org/citations/19874820http://purl.uniprot.org/core/name"Exp Cell Res"xsd:string
http://purl.uniprot.org/citations/19874820http://purl.uniprot.org/core/pages"390-400"xsd:string
http://purl.uniprot.org/citations/19874820http://purl.uniprot.org/core/title"hnRNP M interacts with PSF and p54(nrb) and co-localizes within defined nuclear structures."xsd:string
http://purl.uniprot.org/citations/19874820http://purl.uniprot.org/core/volume"316"xsd:string
http://purl.uniprot.org/citations/19874820http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/19874820
http://purl.uniprot.org/citations/19874820http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/19874820
http://purl.uniprot.org/uniprot/P52272#attribution-2590EC9D77E5F64F8DECC49E7A2F7DAChttp://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/19874820
http://purl.uniprot.org/uniprot/P52272#attribution-AA571AC0BC73C38A74670E0BCEA8DFB7http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/19874820
http://purl.uniprot.org/uniprot/Q15233#attribution-AA571AC0BC73C38A74670E0BCEA8DFB7http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/19874820
http://purl.uniprot.org/uniprot/P23246#attribution-2590EC9D77E5F64F8DECC49E7A2F7DAChttp://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/19874820
http://purl.uniprot.org/uniprot/P23246#attribution-AA571AC0BC73C38A74670E0BCEA8DFB7http://purl.uniprot.org/core/sourcehttp://purl.uniprot.org/citations/19874820
http://purl.uniprot.org/uniprot/#_A0A0S2Z4Z9-mappedCitation-19874820http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19874820
http://purl.uniprot.org/uniprot/#_Q15559-mappedCitation-19874820http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19874820
http://purl.uniprot.org/uniprot/#_A0A8I5ZQ38-mappedCitation-19874820http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19874820
http://purl.uniprot.org/uniprot/#_A0A8I6A4N0-mappedCitation-19874820http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19874820
http://purl.uniprot.org/uniprot/#_A0A0S2Z4E7-mappedCitation-19874820http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19874820
http://purl.uniprot.org/uniprot/#_A0A8I6GC87-mappedCitation-19874820http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19874820