| http://purl.uniprot.org/citations/19896518 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19896518 | http://www.w3.org/2000/01/rdf-schema#comment | "Human leukocyte antigen (HLA) genes play a critical role in host immunity, including vaccine responses. HLA molecules present antigenic peptides to T cells and provide inhibitory signals to NK cells, and polymorphisms within HLA genes allow binding and presentation of a diverse array of self and foreign peptides. Heterozygosity across HLA alleles has been found to play a positive role in host defense for a variety of infections. Homozygosity within one or more HLA loci may restrict this epitope repertoire and limit T-cell responses to infection or vaccination. Here we report that homozygosity within the HLA DPB1 locus is associated with increased levels of rubella-specific IgG, an effect driven by a common allele DPB1*0401. We also show that homozygosity within different HLA class I and class II loci is correlated with variations (but not necessarily decreases) in interleukin (IL)-2, IL-5, and IL-10 secretion after rubella virus stimulation."xsd:string |
| http://purl.uniprot.org/citations/19896518 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.humimm.2009.11.002"xsd:string |
| http://purl.uniprot.org/citations/19896518 | http://purl.uniprot.org/core/author | "Jacobson R.M."xsd:string |
| http://purl.uniprot.org/citations/19896518 | http://purl.uniprot.org/core/author | "Ovsyannikova I.G."xsd:string |
| http://purl.uniprot.org/citations/19896518 | http://purl.uniprot.org/core/author | "Poland G.A."xsd:string |
| http://purl.uniprot.org/citations/19896518 | http://purl.uniprot.org/core/author | "Vierkant R.A."xsd:string |
| http://purl.uniprot.org/citations/19896518 | http://purl.uniprot.org/core/author | "Kennedy R.B."xsd:string |
| http://purl.uniprot.org/citations/19896518 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
| http://purl.uniprot.org/citations/19896518 | http://purl.uniprot.org/core/name | "Hum Immunol"xsd:string |
| http://purl.uniprot.org/citations/19896518 | http://purl.uniprot.org/core/pages | "128-135"xsd:string |
| http://purl.uniprot.org/citations/19896518 | http://purl.uniprot.org/core/title | "Effect of human leukocyte antigen homozygosity on rubella vaccine-induced humoral and cell-mediated immune responses."xsd:string |
| http://purl.uniprot.org/citations/19896518 | http://purl.uniprot.org/core/volume | "71"xsd:string |
| http://purl.uniprot.org/citations/19896518 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/19896518 |
| http://purl.uniprot.org/citations/19896518 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/19896518 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C3H3-mappedCitation-19896518 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19896518 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C3I1-mappedCitation-19896518 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19896518 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C3I5-mappedCitation-19896518 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19896518 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C543-mappedCitation-19896518 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19896518 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C545-mappedCitation-19896518 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19896518 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C548-mappedCitation-19896518 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19896518 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C549-mappedCitation-19896518 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19896518 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C550-mappedCitation-19896518 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19896518 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C551-mappedCitation-19896518 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19896518 |
| http://purl.uniprot.org/uniprot/#_A0A0A7C552-mappedCitation-19896518 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19896518 |