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http://purl.uniprot.org/citations/19897003http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/19897003http://www.w3.org/2000/01/rdf-schema#comment"Killer cell immunoglobulin-like receptors (KIR) control the effector function of natural killer (NK) cells and subsets of T cell, and the genes encoding KIRs are substantially variable among individuals. A majority (58.4%) of Japanese individuals were found to be homozygous for group A KIR haplotypes that encode only a single activating KIR2DS4. Contrarily, most of Japanese patients with Vogt-Koyanagi-Harada (VKH) disease (69.2%), a panuveitis carry Bx genotypes that encode 2-5 activating KIR receptors. Particularly, individuals carrying three activating KIR genes 3DS1, 2DS1, and 2DS5 are more frequent in patient group compared with the controls (42.2% vs 21.4%, p = 0.02). In addition, the inhibitory KIR gene 3DL1 was significantly decreased in patients compared with controls (76.9% vs 98.8%, p = 0.00006). These data suggest that the genotypes encoding a dominant activating KIR receptor repertoire predispose susceptibility to VKH disease."xsd:string
http://purl.uniprot.org/citations/19897003http://purl.org/dc/terms/identifier"doi:10.1016/j.humimm.2009.11.001"xsd:string
http://purl.uniprot.org/citations/19897003http://purl.uniprot.org/core/author"Keino H."xsd:string
http://purl.uniprot.org/citations/19897003http://purl.uniprot.org/core/author"Rajalingam R."xsd:string
http://purl.uniprot.org/citations/19897003http://purl.uniprot.org/core/author"Ashouri E."xsd:string
http://purl.uniprot.org/citations/19897003http://purl.uniprot.org/core/author"Okada A.A."xsd:string
http://purl.uniprot.org/citations/19897003http://purl.uniprot.org/core/author"Levinson R.D."xsd:string
http://purl.uniprot.org/citations/19897003http://purl.uniprot.org/core/date"2010"xsd:gYear
http://purl.uniprot.org/citations/19897003http://purl.uniprot.org/core/name"Hum Immunol"xsd:string
http://purl.uniprot.org/citations/19897003http://purl.uniprot.org/core/pages"192-194"xsd:string
http://purl.uniprot.org/citations/19897003http://purl.uniprot.org/core/title"Killer cell immunoglobulin-like receptor gene-cluster 3DS1-2DL5-2DS1-2DS5 predisposes susceptibility to Vogt-Koyanagi-Harada syndrome in Japanese individuals."xsd:string
http://purl.uniprot.org/citations/19897003http://purl.uniprot.org/core/volume"71"xsd:string
http://purl.uniprot.org/citations/19897003http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/19897003
http://purl.uniprot.org/citations/19897003http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/19897003
http://purl.uniprot.org/uniprot/#_A0A0C4ZLQ8-mappedCitation-19897003http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19897003
http://purl.uniprot.org/uniprot/#_A0A0C4ZN05-mappedCitation-19897003http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19897003
http://purl.uniprot.org/uniprot/#_A0A0C4ZN08-mappedCitation-19897003http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19897003
http://purl.uniprot.org/uniprot/#_A0A0C4ZN11-mappedCitation-19897003http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19897003
http://purl.uniprot.org/uniprot/#_A0A0C4ZN23-mappedCitation-19897003http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19897003
http://purl.uniprot.org/uniprot/#_A0A0C4ZN30-mappedCitation-19897003http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19897003
http://purl.uniprot.org/uniprot/#_A0A0C4ZN31-mappedCitation-19897003http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19897003
http://purl.uniprot.org/uniprot/#_A0A0C4ZNX3-mappedCitation-19897003http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19897003
http://purl.uniprot.org/uniprot/#_A0A0G2JLP2-mappedCitation-19897003http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19897003
http://purl.uniprot.org/uniprot/#_A0A0G2JLQ3-mappedCitation-19897003http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19897003