| http://purl.uniprot.org/citations/19898529 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19898529 | http://www.w3.org/2000/01/rdf-schema#comment | "Chromatin structure is important for the compaction of eukaryotic genomes, thus chromatin modifications play a fundamental role in regulating many cellular processes. The coordinated activities of various chromatin-remodelling and -modifying complexes are crucial in maintaining distinct chromatin neighbourhoods, which in turn ensure appropriate gene expression, as well as DNA replication, repair, and recombination. SWR1-C is an ATP-dependent histone deposition complex for the histone variant H2A.Z, whereas NuA4 is a histone acetyltransferase for histones H4, H2A, and H2A.Z. Together the NuA4 and SWR1-C chromatin-modifying complexes alter the chromatin structure through 3 distinct modifications in yeast: post-translational addition of chemical groups, ATP-dependent chromatin remodelling, and histone variant incorporation. These 2 multi-protein complexes share 4 subunits and function together to regulate the circuitry of H2A.Z biology. The components and functions of both multi-protein complexes are evolutionarily conserved and play important roles in multi-cellular development and cellular differentiation in higher eukaryotes. This review will summarize recent findings about NuA4 and SWR1-C and will focus on the connection between these complexes by investigating their physical and functional interactions through eukaryotic evolution."xsd:string |
| http://purl.uniprot.org/citations/19898529 | http://purl.org/dc/terms/identifier | "doi:10.1139/o09-062"xsd:string |
| http://purl.uniprot.org/citations/19898529 | http://purl.uniprot.org/core/author | "Kobor M.S."xsd:string |
| http://purl.uniprot.org/citations/19898529 | http://purl.uniprot.org/core/author | "Lu P.Y."xsd:string |
| http://purl.uniprot.org/citations/19898529 | http://purl.uniprot.org/core/author | "Levesque N."xsd:string |
| http://purl.uniprot.org/citations/19898529 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19898529 | http://purl.uniprot.org/core/name | "Biochem Cell Biol"xsd:string |
| http://purl.uniprot.org/citations/19898529 | http://purl.uniprot.org/core/pages | "799-815"xsd:string |
| http://purl.uniprot.org/citations/19898529 | http://purl.uniprot.org/core/title | "NuA4 and SWR1-C: two chromatin-modifying complexes with overlapping functions and components."xsd:string |
| http://purl.uniprot.org/citations/19898529 | http://purl.uniprot.org/core/volume | "87"xsd:string |
| http://purl.uniprot.org/citations/19898529 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/19898529 |
| http://purl.uniprot.org/citations/19898529 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/19898529 |
| http://purl.uniprot.org/uniprot/#_P53911-mappedCitation-19898529 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19898529 |
| http://purl.uniprot.org/uniprot/#_P53930-mappedCitation-19898529 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19898529 |
| http://purl.uniprot.org/uniprot/#_P39995-mappedCitation-19898529 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19898529 |
| http://purl.uniprot.org/uniprot/#_Q06707-mappedCitation-19898529 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19898529 |
| http://purl.uniprot.org/uniprot/#_P38326-mappedCitation-19898529 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19898529 |
| http://purl.uniprot.org/uniprot/#_Q03433-mappedCitation-19898529 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19898529 |
| http://purl.uniprot.org/uniprot/#_Q06337-mappedCitation-19898529 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19898529 |
| http://purl.uniprot.org/uniprot/#_P35817-mappedCitation-19898529 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19898529 |
| http://purl.uniprot.org/uniprot/#_Q03388-mappedCitation-19898529 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19898529 |
| http://purl.uniprot.org/uniprot/#_P47128-mappedCitation-19898529 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19898529 |
| http://purl.uniprot.org/uniprot/#_P80428-mappedCitation-19898529 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19898529 |
| http://purl.uniprot.org/uniprot/#_Q03940-mappedCitation-19898529 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19898529 |