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http://purl.uniprot.org/citations/19909739http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/19909739http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/19909739http://www.w3.org/2000/01/rdf-schema#comment"The SYK non-receptor tyrosine kinase is a key effector of immune receptors signaling in hematopoietic cells. Here, we identified and characterized a novel interaction between SYK and the ubiquitin-specific protease 25 (USP25). We report that the second SH2 domain of SYK physically interacts with a tyrosine-rich, C-terminal region of USP25 independently of tyrosine phosphorylation. Moreover, we showed that SYK specifically phosphorylates USP25 and alters its cellular levels. This study thus uncovers a new SYK substrate and reveals a novel SYK function, namely the regulation of USP25 cellular levels."xsd:string
http://purl.uniprot.org/citations/19909739http://purl.org/dc/terms/identifier"doi:10.1016/j.yexcr.2009.10.023"xsd:string
http://purl.uniprot.org/citations/19909739http://purl.org/dc/terms/identifier"doi:10.1016/j.yexcr.2009.10.023"xsd:string
http://purl.uniprot.org/citations/19909739http://purl.uniprot.org/core/author"Benarous R."xsd:string
http://purl.uniprot.org/citations/19909739http://purl.uniprot.org/core/author"Benarous R."xsd:string
http://purl.uniprot.org/citations/19909739http://purl.uniprot.org/core/author"Reverdy C."xsd:string
http://purl.uniprot.org/citations/19909739http://purl.uniprot.org/core/author"Reverdy C."xsd:string
http://purl.uniprot.org/citations/19909739http://purl.uniprot.org/core/author"Colland F."xsd:string
http://purl.uniprot.org/citations/19909739http://purl.uniprot.org/core/author"Colland F."xsd:string
http://purl.uniprot.org/citations/19909739http://purl.uniprot.org/core/author"Daviet L."xsd:string
http://purl.uniprot.org/citations/19909739http://purl.uniprot.org/core/author"Daviet L."xsd:string
http://purl.uniprot.org/citations/19909739http://purl.uniprot.org/core/author"Cholay M."xsd:string
http://purl.uniprot.org/citations/19909739http://purl.uniprot.org/core/author"Cholay M."xsd:string
http://purl.uniprot.org/citations/19909739http://purl.uniprot.org/core/date"2010"xsd:gYear
http://purl.uniprot.org/citations/19909739http://purl.uniprot.org/core/date"2010"xsd:gYear
http://purl.uniprot.org/citations/19909739http://purl.uniprot.org/core/name"Exp. Cell Res."xsd:string
http://purl.uniprot.org/citations/19909739http://purl.uniprot.org/core/name"Exp. Cell Res."xsd:string
http://purl.uniprot.org/citations/19909739http://purl.uniprot.org/core/pages"667-675"xsd:string
http://purl.uniprot.org/citations/19909739http://purl.uniprot.org/core/pages"667-675"xsd:string
http://purl.uniprot.org/citations/19909739http://purl.uniprot.org/core/title"Functional interaction between the ubiquitin-specific protease 25 and the SYK tyrosine kinase."xsd:string
http://purl.uniprot.org/citations/19909739http://purl.uniprot.org/core/title"Functional interaction between the ubiquitin-specific protease 25 and the SYK tyrosine kinase."xsd:string
http://purl.uniprot.org/citations/19909739http://purl.uniprot.org/core/volume"316"xsd:string
http://purl.uniprot.org/citations/19909739http://purl.uniprot.org/core/volume"316"xsd:string