| http://purl.uniprot.org/citations/19924516 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19924516 | http://www.w3.org/2000/01/rdf-schema#comment | "FEZ1 was initially described as a neuronal protein that influences axonal development and cell polarization. CLASP2 and NEK1 proteins are present in a centrosomal complex and participate in cell cycle and cell division mechanisms, but their functions were always described individually. Here, we report that NEK1 and CLASP2 colocalize with FEZ1 in a perinuclear region in mammalian cells, and observed that coiled-coil interactions occur between FEZ1/CLASP2 and FEZ1/NEK1 in vitro. These three proteins colocalize and interact with endogenous gamma-tubulin. Furthermore, we found that CLASP2 is phosphorylated and interacts with active PKC isoforms, and that FEZ1/CLASP2 colocalization is inhibited by PMA treatment. Our results provide evidence that these three proteins cooperate in centrosomal functions and open new directions for future studies."xsd:string |
| http://purl.uniprot.org/citations/19924516 | http://purl.org/dc/terms/identifier | "doi:10.1007/s11010-009-0317-9"xsd:string |
| http://purl.uniprot.org/citations/19924516 | http://purl.uniprot.org/core/author | "Kobarg J."xsd:string |
| http://purl.uniprot.org/citations/19924516 | http://purl.uniprot.org/core/author | "Alborghetti M.R."xsd:string |
| http://purl.uniprot.org/citations/19924516 | http://purl.uniprot.org/core/author | "Lanza D.C."xsd:string |
| http://purl.uniprot.org/citations/19924516 | http://purl.uniprot.org/core/author | "Meirelles G.V."xsd:string |
| http://purl.uniprot.org/citations/19924516 | http://purl.uniprot.org/core/author | "Lenz G."xsd:string |
| http://purl.uniprot.org/citations/19924516 | http://purl.uniprot.org/core/author | "Abrile C.H."xsd:string |
| http://purl.uniprot.org/citations/19924516 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
| http://purl.uniprot.org/citations/19924516 | http://purl.uniprot.org/core/name | "Mol Cell Biochem"xsd:string |
| http://purl.uniprot.org/citations/19924516 | http://purl.uniprot.org/core/pages | "35-45"xsd:string |
| http://purl.uniprot.org/citations/19924516 | http://purl.uniprot.org/core/title | "FEZ1 interacts with CLASP2 and NEK1 through coiled-coil regions and their cellular colocalization suggests centrosomal functions and regulation by PKC."xsd:string |
| http://purl.uniprot.org/citations/19924516 | http://purl.uniprot.org/core/volume | "338"xsd:string |
| http://purl.uniprot.org/citations/19924516 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/19924516 |
| http://purl.uniprot.org/citations/19924516 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/19924516 |
| http://purl.uniprot.org/uniprot/#_Q07A19-mappedCitation-19924516 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19924516 |
| http://purl.uniprot.org/uniprot/#_Q07A20-mappedCitation-19924516 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19924516 |
| http://purl.uniprot.org/uniprot/#_B4DF74-mappedCitation-19924516 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19924516 |
| http://purl.uniprot.org/uniprot/#_B4DG03-mappedCitation-19924516 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19924516 |
| http://purl.uniprot.org/uniprot/#_B4DKG5-mappedCitation-19924516 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19924516 |
| http://purl.uniprot.org/uniprot/#_B3KR06-mappedCitation-19924516 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19924516 |
| http://purl.uniprot.org/uniprot/#_B4DM73-mappedCitation-19924516 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19924516 |
| http://purl.uniprot.org/uniprot/#_E7ERI8-mappedCitation-19924516 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19924516 |
| http://purl.uniprot.org/uniprot/#_Q15453-mappedCitation-19924516 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19924516 |