| http://purl.uniprot.org/citations/19941829 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19941829 | http://www.w3.org/2000/01/rdf-schema#comment | "Genetic recombination ensures proper chromosome segregation during meiosis and is essential for genome stability and tumor suppression. DNA synthesis after Rad51-mediated DNA strand invasion is a crucial step during recombination. PCNA is known as the processivity clamp for DNA polymerases. Here, we report the surprising observation that PCNA is specifically required to initiate recombination-associated DNA synthesis in the extension of the 3' end of the invading strand in a D loop. We show using a reconstituted system of yeast Rad51, Rad54, RPA, PCNA, RFC, and DNA polymerase delta that loading of PCNA by RFC targets DNA polymerase delta to the D loop formed by Rad51 protein, allowing efficient utilization of the invading 3' end and processive DNA synthesis. We conclude that PCNA has a specific role in the initiation of recombination-associated DNA synthesis and that DNA polymerase delta promotes recombination-associated DNA synthesis."xsd:string |
| http://purl.uniprot.org/citations/19941829 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.molcel.2009.09.036"xsd:string |
| http://purl.uniprot.org/citations/19941829 | http://purl.uniprot.org/core/author | "Li X."xsd:string |
| http://purl.uniprot.org/citations/19941829 | http://purl.uniprot.org/core/author | "Burgers P.M."xsd:string |
| http://purl.uniprot.org/citations/19941829 | http://purl.uniprot.org/core/author | "Heyer W.D."xsd:string |
| http://purl.uniprot.org/citations/19941829 | http://purl.uniprot.org/core/author | "Stith C.M."xsd:string |
| http://purl.uniprot.org/citations/19941829 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19941829 | http://purl.uniprot.org/core/name | "Mol Cell"xsd:string |
| http://purl.uniprot.org/citations/19941829 | http://purl.uniprot.org/core/pages | "704-713"xsd:string |
| http://purl.uniprot.org/citations/19941829 | http://purl.uniprot.org/core/title | "PCNA is required for initiation of recombination-associated DNA synthesis by DNA polymerase delta."xsd:string |
| http://purl.uniprot.org/citations/19941829 | http://purl.uniprot.org/core/volume | "36"xsd:string |
| http://purl.uniprot.org/citations/19941829 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/19941829 |
| http://purl.uniprot.org/citations/19941829 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/19941829 |
| http://purl.uniprot.org/uniprot/#_P15436-mappedCitation-19941829 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19941829 |
| http://purl.uniprot.org/uniprot/#_P54132-mappedCitation-19941829 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19941829 |
| http://purl.uniprot.org/uniprot/#_Q07864-mappedCitation-19941829 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19941829 |
| http://purl.uniprot.org/uniprot/#_Q14191-mappedCitation-19941829 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19941829 |
| http://purl.uniprot.org/uniprot/#_Q15054-mappedCitation-19941829 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19941829 |
| http://purl.uniprot.org/uniprot/#_A0A6L0YQ40-mappedCitation-19941829 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19941829 |
| http://purl.uniprot.org/uniprot/#_A0A6B7JGY6-mappedCitation-19941829 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19941829 |
| http://purl.uniprot.org/uniprot/#_O15315-mappedCitation-19941829 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19941829 |
| http://purl.uniprot.org/uniprot/#_P49005-mappedCitation-19941829 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19941829 |
| http://purl.uniprot.org/uniprot/#_P0CG47-mappedCitation-19941829 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19941829 |
| http://purl.uniprot.org/uniprot/#_P0CG48-mappedCitation-19941829 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19941829 |