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http://purl.uniprot.org/citations/19944079http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/19944079http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/19944079http://www.w3.org/2000/01/rdf-schema#comment"Lipoproteins are well known virulence factors of bacterial pathogens in general and of Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis, in particular. Lipoprotein lipidation between Gram-positive and Gram-negative bacteria differs significantly as these are di- and triacylated, respectively. Little is known about the lipid anchor of mycobacterial lipoproteins. We reported recently that mycobacterial LppX, a lipoprotein involved in synthesis of cell wall components is triacylated, although mycobacteria are classified as GC-rich Gram-positive bacteria. We here exploited the model organism Mycobacterium smegmatis for the expression of Mtb LprF and characterized N-terminal modifications at the molecular level. LprF is a putative lipoprotein of Mtb involved in signaling of potassium-dependent osmotic stress. LprF is extensively modified in a mycobacterium-specific manner by a thioether-linked diacylglyceryl residue with one ester-bound tuberculostearic- and one C16:0 fatty acid and additionally by a third N-linked C16:0 fatty acid, and a hexose."xsd:string
http://purl.uniprot.org/citations/19944079http://purl.org/dc/terms/identifier"doi:10.1016/j.bbrc.2009.11.120"xsd:string
http://purl.uniprot.org/citations/19944079http://purl.org/dc/terms/identifier"doi:10.1016/j.bbrc.2009.11.120"xsd:string
http://purl.uniprot.org/citations/19944079http://purl.uniprot.org/core/author"Hunziker P."xsd:string
http://purl.uniprot.org/citations/19944079http://purl.uniprot.org/core/author"Hunziker P."xsd:string
http://purl.uniprot.org/citations/19944079http://purl.uniprot.org/core/author"Sander P."xsd:string
http://purl.uniprot.org/citations/19944079http://purl.uniprot.org/core/author"Sander P."xsd:string
http://purl.uniprot.org/citations/19944079http://purl.uniprot.org/core/author"Keller P.M."xsd:string
http://purl.uniprot.org/citations/19944079http://purl.uniprot.org/core/author"Keller P.M."xsd:string
http://purl.uniprot.org/citations/19944079http://purl.uniprot.org/core/author"Grau T."xsd:string
http://purl.uniprot.org/citations/19944079http://purl.uniprot.org/core/author"Grau T."xsd:string
http://purl.uniprot.org/citations/19944079http://purl.uniprot.org/core/author"Auchli Y."xsd:string
http://purl.uniprot.org/citations/19944079http://purl.uniprot.org/core/author"Auchli Y."xsd:string
http://purl.uniprot.org/citations/19944079http://purl.uniprot.org/core/author"Bruelle J.K."xsd:string
http://purl.uniprot.org/citations/19944079http://purl.uniprot.org/core/author"Bruelle J.K."xsd:string
http://purl.uniprot.org/citations/19944079http://purl.uniprot.org/core/author"Burri R."xsd:string
http://purl.uniprot.org/citations/19944079http://purl.uniprot.org/core/author"Burri R."xsd:string
http://purl.uniprot.org/citations/19944079http://purl.uniprot.org/core/author"Polsfuss S."xsd:string
http://purl.uniprot.org/citations/19944079http://purl.uniprot.org/core/author"Polsfuss S."xsd:string
http://purl.uniprot.org/citations/19944079http://purl.uniprot.org/core/author"Tschumi A."xsd:string
http://purl.uniprot.org/citations/19944079http://purl.uniprot.org/core/author"Tschumi A."xsd:string
http://purl.uniprot.org/citations/19944079http://purl.uniprot.org/core/date"2010"xsd:gYear
http://purl.uniprot.org/citations/19944079http://purl.uniprot.org/core/date"2010"xsd:gYear