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http://purl.uniprot.org/citations/19965582http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/19965582http://www.w3.org/2000/01/rdf-schema#comment"Our previous work indicated that apolipoprotein (apo) E4 assumes a more expanded conformation in the postprandial period. The postprandial state is characterized by increased VLDL lipolysis. In this article, we tested the hypothesis that VLDL lipolysis products increase VLDL particle fluidity, which mediates expansion of apoE4 on the VLDL particle. Plasma from healthy subjects was collected before and after a moderately high-fat meal and incubated with nitroxyl-spin labeled apoE. ApoE conformation was examined by electron paramagnetic resonance spectroscopy using targeted spin probes on cysteines introduced in the N-terminal (S76C) and C-terminal (A241C) domains. Further, we synthesized a novel nitroxyl spin-labeled cholesterol analog, which gave insight into lipoprotein particle fluidity. Our data revealed that the order of lipoprotein fluidity was HDL approximately LDLxsd:string
http://purl.uniprot.org/citations/19965582http://purl.org/dc/terms/identifier"doi:10.1194/jlr.m000406"xsd:string
http://purl.uniprot.org/citations/19965582http://purl.uniprot.org/core/author"Voss J.C."xsd:string
http://purl.uniprot.org/citations/19965582http://purl.uniprot.org/core/author"Weisgraber K.H."xsd:string
http://purl.uniprot.org/citations/19965582http://purl.uniprot.org/core/author"Hatters D.M."xsd:string
http://purl.uniprot.org/citations/19965582http://purl.uniprot.org/core/author"Budamagunta M.S."xsd:string
http://purl.uniprot.org/citations/19965582http://purl.uniprot.org/core/author"Tetali S.D."xsd:string
http://purl.uniprot.org/citations/19965582http://purl.uniprot.org/core/author"Rutledge J.C."xsd:string
http://purl.uniprot.org/citations/19965582http://purl.uniprot.org/core/author"Hideg K."xsd:string
http://purl.uniprot.org/citations/19965582http://purl.uniprot.org/core/author"Kalai T."xsd:string
http://purl.uniprot.org/citations/19965582http://purl.uniprot.org/core/author"Simion C."xsd:string
http://purl.uniprot.org/citations/19965582http://purl.uniprot.org/core/author"den Hartigh L.J."xsd:string
http://purl.uniprot.org/citations/19965582http://purl.uniprot.org/core/date"2010"xsd:gYear
http://purl.uniprot.org/citations/19965582http://purl.uniprot.org/core/name"J Lipid Res"xsd:string
http://purl.uniprot.org/citations/19965582http://purl.uniprot.org/core/pages"1273-1283"xsd:string
http://purl.uniprot.org/citations/19965582http://purl.uniprot.org/core/title"VLDL lipolysis products increase VLDL fluidity and convert apolipoprotein E4 into a more expanded conformation."xsd:string
http://purl.uniprot.org/citations/19965582http://purl.uniprot.org/core/volume"51"xsd:string
http://purl.uniprot.org/citations/19965582http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/19965582
http://purl.uniprot.org/citations/19965582http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/19965582
http://purl.uniprot.org/uniprot/#_A0A0S2Z3B1-mappedCitation-19965582http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19965582
http://purl.uniprot.org/uniprot/#_A0A0S2Z3V0-mappedCitation-19965582http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19965582
http://purl.uniprot.org/uniprot/#_A0A0S2Z3D5-mappedCitation-19965582http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19965582
http://purl.uniprot.org/uniprot/#_A0A0S2Z3J5-mappedCitation-19965582http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19965582
http://purl.uniprot.org/uniprot/#_A0A346DBY2-mappedCitation-19965582http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19965582