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http://purl.uniprot.org/citations/19966800http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/19966800http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/19966800http://www.w3.org/2000/01/rdf-schema#comment"The CagA protein of Helicobacter pylori interacts with numerous cellular factors and is associated with increased virulence and risk of gastric carcinoma. We present here the cocrystal structure of a subdomain of CagA with the human kinase PAR1b/MARK2, revealing that a CagA peptide mimics substrates of this kinase family, resembling eukaryotic protein kinase inhibitors. Mutagenesis of conserved residues central to this interaction renders CagA inactive as an inhibitor of MARK2."xsd:string
http://purl.uniprot.org/citations/19966800http://purl.org/dc/terms/identifier"doi:10.1038/nsmb.1705"xsd:string
http://purl.uniprot.org/citations/19966800http://purl.org/dc/terms/identifier"doi:10.1038/nsmb.1705"xsd:string
http://purl.uniprot.org/citations/19966800http://purl.uniprot.org/core/author"Chait B.T."xsd:string
http://purl.uniprot.org/citations/19966800http://purl.uniprot.org/core/author"Chait B.T."xsd:string
http://purl.uniprot.org/citations/19966800http://purl.uniprot.org/core/author"Miller M.C."xsd:string
http://purl.uniprot.org/citations/19966800http://purl.uniprot.org/core/author"Miller M.C."xsd:string
http://purl.uniprot.org/citations/19966800http://purl.uniprot.org/core/author"Stein M."xsd:string
http://purl.uniprot.org/citations/19966800http://purl.uniprot.org/core/author"Stein M."xsd:string
http://purl.uniprot.org/citations/19966800http://purl.uniprot.org/core/author"Stebbins C.E."xsd:string
http://purl.uniprot.org/citations/19966800http://purl.uniprot.org/core/author"Stebbins C.E."xsd:string
http://purl.uniprot.org/citations/19966800http://purl.uniprot.org/core/author"Nesic D."xsd:string
http://purl.uniprot.org/citations/19966800http://purl.uniprot.org/core/author"Nesic D."xsd:string
http://purl.uniprot.org/citations/19966800http://purl.uniprot.org/core/author"Quinkert Z.T."xsd:string
http://purl.uniprot.org/citations/19966800http://purl.uniprot.org/core/author"Quinkert Z.T."xsd:string
http://purl.uniprot.org/citations/19966800http://purl.uniprot.org/core/date"2010"xsd:gYear
http://purl.uniprot.org/citations/19966800http://purl.uniprot.org/core/date"2010"xsd:gYear
http://purl.uniprot.org/citations/19966800http://purl.uniprot.org/core/name"Nat. Struct. Mol. Biol."xsd:string
http://purl.uniprot.org/citations/19966800http://purl.uniprot.org/core/name"Nat. Struct. Mol. Biol."xsd:string
http://purl.uniprot.org/citations/19966800http://purl.uniprot.org/core/pages"130-132"xsd:string
http://purl.uniprot.org/citations/19966800http://purl.uniprot.org/core/pages"130-132"xsd:string
http://purl.uniprot.org/citations/19966800http://purl.uniprot.org/core/title"Helicobacter pylori CagA inhibits PAR1-MARK family kinases by mimicking host substrates."xsd:string
http://purl.uniprot.org/citations/19966800http://purl.uniprot.org/core/title"Helicobacter pylori CagA inhibits PAR1-MARK family kinases by mimicking host substrates."xsd:string