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http://purl.uniprot.org/citations/19968649http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/19968649http://www.w3.org/2000/01/rdf-schema#comment"beta, beta-carotene-9', 10'-dioxygenase (BCO2) plays a role in cleaving beta-carotene eccentrically, and may be involved in the control of adipose and milk colour in cattle. The bovine BCO2 gene was sequenced as a potential candidate gene for a beef fat colour QTL on chromosome (BTA) 15. A single nucleotide base change located in exon 3 causes the substitution of a stop codon (encoded by the A allele) for tryptophan(80) (encoded by the G allele) (c. 240G>A, p.Trp80stop, referred to herein as SNP W80X). Association analysis showed significant differences in subcutaneous fat colour and beta-carotene concentration amongst cattle with different BCO2 genotypes. Animals with the BCO2 AA genotype had more yellow beef fat and a higher beta-carotene concentration in adipose tissues than those with the GA or GG genotype. QTL mapping analysis with the BCO2 SNP W80X fitted as a fixed effect confirmed that this SNP is likely to represent the quantitative trait nucleotide (QTN) for the fat colour-related traits on BTA 15. Moreover, animals with the AA genotype had yellower milk colour and a higher concentration of beta-carotene in the milk."xsd:string
http://purl.uniprot.org/citations/19968649http://purl.org/dc/terms/identifier"doi:10.1111/j.1365-2052.2009.01990.x"xsd:string
http://purl.uniprot.org/citations/19968649http://purl.uniprot.org/core/author"Tian R."xsd:string
http://purl.uniprot.org/citations/19968649http://purl.uniprot.org/core/author"Morris C.A."xsd:string
http://purl.uniprot.org/citations/19968649http://purl.uniprot.org/core/author"Bottema C.D."xsd:string
http://purl.uniprot.org/citations/19968649http://purl.uniprot.org/core/author"Cullen N.G."xsd:string
http://purl.uniprot.org/citations/19968649http://purl.uniprot.org/core/author"Pitchford W.S."xsd:string
http://purl.uniprot.org/citations/19968649http://purl.uniprot.org/core/date"2010"xsd:gYear
http://purl.uniprot.org/citations/19968649http://purl.uniprot.org/core/name"Anim Genet"xsd:string
http://purl.uniprot.org/citations/19968649http://purl.uniprot.org/core/pages"253-259"xsd:string
http://purl.uniprot.org/citations/19968649http://purl.uniprot.org/core/title"Genetic variation in the beta, beta-carotene-9', 10'-dioxygenase gene and association with fat colour in bovine adipose tissue and milk."xsd:string
http://purl.uniprot.org/citations/19968649http://purl.uniprot.org/core/volume"41"xsd:string
http://purl.uniprot.org/citations/19968649http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/19968649
http://purl.uniprot.org/citations/19968649http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/19968649
http://purl.uniprot.org/uniprot/#_A7E341-mappedCitation-19968649http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19968649
http://purl.uniprot.org/uniprot/#_F1N2Z9-mappedCitation-19968649http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/19968649
http://purl.uniprot.org/uniprot/F1N2Z9http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/19968649
http://purl.uniprot.org/uniprot/A7E341http://purl.uniprot.org/core/mappedCitationhttp://purl.uniprot.org/citations/19968649