| http://purl.uniprot.org/citations/19995935 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/19995935 | http://www.w3.org/2000/01/rdf-schema#comment | "Successful completion of cytokinesis relies on addition of new membrane, and requires the recycling endosome regulator Rab11, which localizes to the midzone. Despite the critical role of Rab11 in this process, little is known about the formation and composition of Rab11-containing organelles. Here, we identify the phosphatidylinositol (PI) 4-kinase III beta four wheel drive (Fwd) as a key regulator of Rab11 during cytokinesis in Drosophila melanogaster spermatocytes. We show Fwd is required for synthesis of PI 4-phosphate (PI4P) on Golgi membranes and for formation of PI4P-containing secretory organelles that localize to the midzone. Fwd binds and colocalizes with Rab11 on Golgi membranes, and is required for localization of Rab11 in dividing cells. A kinase-dead version of Fwd also binds Rab11 and partially restores cytokinesis to fwd mutant flies. Moreover, activated Rab11 partially suppresses loss of fwd. Our data suggest Fwd plays catalytic and noncatalytic roles in regulating Rab11 during cytokinesis."xsd:string |
| http://purl.uniprot.org/citations/19995935 | http://purl.org/dc/terms/identifier | "doi:10.1083/jcb.200908107"xsd:string |
| http://purl.uniprot.org/citations/19995935 | http://purl.uniprot.org/core/author | "Kim Y.J."xsd:string |
| http://purl.uniprot.org/citations/19995935 | http://purl.uniprot.org/core/author | "Szentpetery Z."xsd:string |
| http://purl.uniprot.org/citations/19995935 | http://purl.uniprot.org/core/author | "Brill J.A."xsd:string |
| http://purl.uniprot.org/citations/19995935 | http://purl.uniprot.org/core/author | "Polevoy G."xsd:string |
| http://purl.uniprot.org/citations/19995935 | http://purl.uniprot.org/core/author | "Wei H.C."xsd:string |
| http://purl.uniprot.org/citations/19995935 | http://purl.uniprot.org/core/author | "Wong R."xsd:string |
| http://purl.uniprot.org/citations/19995935 | http://purl.uniprot.org/core/author | "Balla T."xsd:string |
| http://purl.uniprot.org/citations/19995935 | http://purl.uniprot.org/core/author | "Steinbach S.K."xsd:string |
| http://purl.uniprot.org/citations/19995935 | http://purl.uniprot.org/core/author | "Goldbach P."xsd:string |
| http://purl.uniprot.org/citations/19995935 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/19995935 | http://purl.uniprot.org/core/name | "J Cell Biol"xsd:string |
| http://purl.uniprot.org/citations/19995935 | http://purl.uniprot.org/core/pages | "847-858"xsd:string |
| http://purl.uniprot.org/citations/19995935 | http://purl.uniprot.org/core/title | "Dual roles for the Drosophila PI 4-kinase four wheel drive in localizing Rab11 during cytokinesis."xsd:string |
| http://purl.uniprot.org/citations/19995935 | http://purl.uniprot.org/core/volume | "187"xsd:string |
| http://purl.uniprot.org/citations/19995935 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/19995935 |
| http://purl.uniprot.org/citations/19995935 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/19995935 |
| http://purl.uniprot.org/uniprot/Q9W0R8#attribution-4D689A25D3356120A7C4A4EA563C150C | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/19995935 |
| http://purl.uniprot.org/uniprot/Q9W0R8#attribution-EAEC654CFC42B1C4D064926C01028981 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/19995935 |
| http://purl.uniprot.org/uniprot/Q9BKJ2#attribution-4D689A25D3356120A7C4A4EA563C150C | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/19995935 |
| http://purl.uniprot.org/uniprot/Q9BKJ2#attribution-EAEC654CFC42B1C4D064926C01028981 | http://purl.uniprot.org/core/source | http://purl.uniprot.org/citations/19995935 |
| http://purl.uniprot.org/uniprot/#_P54357-mappedCitation-19995935 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19995935 |
| http://purl.uniprot.org/uniprot/#_P61857-mappedCitation-19995935 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/19995935 |