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http://purl.uniprot.org/citations/19997590http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/19997590http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/19997590http://www.w3.org/2000/01/rdf-schema#comment"The proper function of mammalian mitochondria necessitates a coordinated expression of both nuclear and mitochondrial genes, most likely due to the co-evolution of nuclear and mitochondrial genomes. The non-protein coding regions of mitochondrial DNA (mtDNA) including the D-loop, tRNA and rRNA genes form a major component of this regulated expression unit. Here we present comparative analyses of the non-protein-coding regions from 27 Rattus norvegicus mtDNA sequences. There were two variable positions in 12S rRNA, 20 in 16S rRNA, eight within the tRNA genes and 13 in the D-loop. Only one of the three neutrality tests used demonstrated statistically significant evidence for selection in 16S rRNA and tRNA-Cys. Based on our analyses of conserved sequences, we propose that some of the variable nucleotide positions identified in 16S rRNA and tRNA-Cys, and the D-loop might be important for mitochondrial function and its regulation."xsd:string
http://purl.uniprot.org/citations/19997590http://purl.org/dc/terms/identifier"doi:10.1371/journal.pone.0008148"xsd:string
http://purl.uniprot.org/citations/19997590http://purl.org/dc/terms/identifier"doi:10.1371/journal.pone.0008148"xsd:string
http://purl.uniprot.org/citations/19997590http://purl.uniprot.org/core/author"Luthman H."xsd:string
http://purl.uniprot.org/citations/19997590http://purl.uniprot.org/core/author"Luthman H."xsd:string
http://purl.uniprot.org/citations/19997590http://purl.uniprot.org/core/author"Abhyankar A."xsd:string
http://purl.uniprot.org/citations/19997590http://purl.uniprot.org/core/author"Abhyankar A."xsd:string
http://purl.uniprot.org/citations/19997590http://purl.uniprot.org/core/author"Park H.B."xsd:string
http://purl.uniprot.org/citations/19997590http://purl.uniprot.org/core/author"Park H.-B."xsd:string
http://purl.uniprot.org/citations/19997590http://purl.uniprot.org/core/author"Tonolo G."xsd:string
http://purl.uniprot.org/citations/19997590http://purl.uniprot.org/core/author"Tonolo G."xsd:string
http://purl.uniprot.org/citations/19997590http://purl.uniprot.org/core/date"2009"xsd:gYear
http://purl.uniprot.org/citations/19997590http://purl.uniprot.org/core/date"2009"xsd:gYear
http://purl.uniprot.org/citations/19997590http://purl.uniprot.org/core/name"PLoS ONE"xsd:string
http://purl.uniprot.org/citations/19997590http://purl.uniprot.org/core/name"PLoS One"xsd:string
http://purl.uniprot.org/citations/19997590http://purl.uniprot.org/core/pages"e8148"xsd:string
http://purl.uniprot.org/citations/19997590http://purl.uniprot.org/core/pages"e8148"xsd:string
http://purl.uniprot.org/citations/19997590http://purl.uniprot.org/core/title"Comparative sequence analysis of the non-protein-coding mitochondrial DNA of inbred rat strains."xsd:string
http://purl.uniprot.org/citations/19997590http://purl.uniprot.org/core/title"Comparative sequence analysis of the non-protein-coding mitochondrial DNA of inbred rat strains."xsd:string
http://purl.uniprot.org/citations/19997590http://purl.uniprot.org/core/volume"4"xsd:string
http://purl.uniprot.org/citations/19997590http://purl.uniprot.org/core/volume"4"xsd:string
http://purl.uniprot.org/citations/19997590http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/19997590
http://purl.uniprot.org/citations/19997590http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/19997590