| http://purl.uniprot.org/citations/20005841 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/20005841 | http://www.w3.org/2000/01/rdf-schema#comment | "Ribosomal processing requires a series of endo- and exonucleolytic steps for the production of mature ribosomes, of which most have been described. To ensure ribosome synthesis, 3' end formation of rRNA uses multiple nucleases acting in parallel; however, a similar parallel mechanism had not been described for 5' end maturation. Here, we identify Rrp17p as a previously unidentified 5'-3' exonuclease essential for ribosome biogenesis, functioning with Rat1p in a parallel processing pathway analogous to that of 3' end formation. Rrp17p is required for efficient exonuclease digestion of the mature 5' ends of 5.8S(S) and 25S rRNAs, contains a catalytic domain close to its N terminus, and is highly conserved among higher eukaryotes, being a member of a family of exonucleases. We show that Rrp17p binds late pre-60S ribosomes, accompanying them from the nucleolus to the nuclear periphery, and provide evidence for physical and functional links between late 60S subunit processing and export."xsd:string |
| http://purl.uniprot.org/citations/20005841 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.molcel.2009.11.011"xsd:string |
| http://purl.uniprot.org/citations/20005841 | http://purl.uniprot.org/core/author | "Chait B.T."xsd:string |
| http://purl.uniprot.org/citations/20005841 | http://purl.uniprot.org/core/author | "Singer R.H."xsd:string |
| http://purl.uniprot.org/citations/20005841 | http://purl.uniprot.org/core/author | "Tollervey D."xsd:string |
| http://purl.uniprot.org/citations/20005841 | http://purl.uniprot.org/core/author | "Rout M.P."xsd:string |
| http://purl.uniprot.org/citations/20005841 | http://purl.uniprot.org/core/author | "Oeffinger M."xsd:string |
| http://purl.uniprot.org/citations/20005841 | http://purl.uniprot.org/core/author | "Zenklusen D."xsd:string |
| http://purl.uniprot.org/citations/20005841 | http://purl.uniprot.org/core/author | "Ferguson A."xsd:string |
| http://purl.uniprot.org/citations/20005841 | http://purl.uniprot.org/core/author | "Wei K.E."xsd:string |
| http://purl.uniprot.org/citations/20005841 | http://purl.uniprot.org/core/author | "El Hage A."xsd:string |
| http://purl.uniprot.org/citations/20005841 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/20005841 | http://purl.uniprot.org/core/name | "Mol Cell"xsd:string |
| http://purl.uniprot.org/citations/20005841 | http://purl.uniprot.org/core/pages | "768-781"xsd:string |
| http://purl.uniprot.org/citations/20005841 | http://purl.uniprot.org/core/title | "Rrp17p is a eukaryotic exonuclease required for 5' end processing of Pre-60S ribosomal RNA."xsd:string |
| http://purl.uniprot.org/citations/20005841 | http://purl.uniprot.org/core/volume | "36"xsd:string |
| http://purl.uniprot.org/citations/20005841 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/20005841 |
| http://purl.uniprot.org/citations/20005841 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/20005841 |
| http://purl.uniprot.org/uniprot/#_A0A6A5Q2X9-mappedCitation-20005841 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20005841 |
| http://purl.uniprot.org/uniprot/#_P22147-mappedCitation-20005841 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20005841 |
| http://purl.uniprot.org/uniprot/#_Q04031-mappedCitation-20005841 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20005841 |
| http://purl.uniprot.org/uniprot/#_Q02792-mappedCitation-20005841 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20005841 |
| http://purl.uniprot.org/uniprot/Q02792 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/20005841 |
| http://purl.uniprot.org/uniprot/P22147 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/20005841 |