| http://purl.uniprot.org/citations/20008528 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/20008528 | http://www.w3.org/2000/01/rdf-schema#comment | "CD103(+) dendritic cells (DCs) in nonlymphoid tissues are specialized in the cross-presentation of cell-associated antigens. However, little is known about the mechanisms that regulate the development of these cells. We show that two populations of CD11c(+)MHCII(+) cells separated on the basis of CD103 and CD11b expression coexist in most nonlymphoid tissues with the exception of the lamina propria. CD103(+) DCs are related to lymphoid organ CD8(+) DCs in that they are derived exclusively from pre-DCs under the control of fms-like tyrosine kinase 3 (Flt3) ligand, inhibitor of DNA protein 2 (Id2), and IFN regulatory protein 8 (IRF8). In contrast, lamina propria CD103(+) DCs express CD11b and develop independently of Id2 and IRF8. The other population of CD11c(+)MHCII(+) cells in tissues, which is CD103(-)CD11b(+), is heterogenous and depends on both Flt3 and MCSF-R. Our results reveal that nonlymphoid tissue CD103(+) DCs and lymphoid organ CD8(+) DCs derive from the same precursor and follow a related differentiation program."xsd:string |
| http://purl.uniprot.org/citations/20008528 | http://purl.org/dc/terms/identifier | "doi:10.1084/jem.20091756"xsd:string |
| http://purl.uniprot.org/citations/20008528 | http://purl.uniprot.org/core/author | "Price J."xsd:string |
| http://purl.uniprot.org/citations/20008528 | http://purl.uniprot.org/core/author | "Liu K."xsd:string |
| http://purl.uniprot.org/citations/20008528 | http://purl.uniprot.org/core/author | "Yin N."xsd:string |
| http://purl.uniprot.org/citations/20008528 | http://purl.uniprot.org/core/author | "Ginhoux F."xsd:string |
| http://purl.uniprot.org/citations/20008528 | http://purl.uniprot.org/core/author | "Stanley E.R."xsd:string |
| http://purl.uniprot.org/citations/20008528 | http://purl.uniprot.org/core/author | "Lira S.A."xsd:string |
| http://purl.uniprot.org/citations/20008528 | http://purl.uniprot.org/core/author | "Bogunovic M."xsd:string |
| http://purl.uniprot.org/citations/20008528 | http://purl.uniprot.org/core/author | "Merad M."xsd:string |
| http://purl.uniprot.org/citations/20008528 | http://purl.uniprot.org/core/author | "Nussenzweig M."xsd:string |
| http://purl.uniprot.org/citations/20008528 | http://purl.uniprot.org/core/author | "Hashimoto D."xsd:string |
| http://purl.uniprot.org/citations/20008528 | http://purl.uniprot.org/core/author | "Bromberg J."xsd:string |
| http://purl.uniprot.org/citations/20008528 | http://purl.uniprot.org/core/author | "Helft J."xsd:string |
| http://purl.uniprot.org/citations/20008528 | http://purl.uniprot.org/core/author | "Greter M."xsd:string |
| http://purl.uniprot.org/citations/20008528 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
| http://purl.uniprot.org/citations/20008528 | http://purl.uniprot.org/core/name | "J Exp Med"xsd:string |
| http://purl.uniprot.org/citations/20008528 | http://purl.uniprot.org/core/pages | "3115-3130"xsd:string |
| http://purl.uniprot.org/citations/20008528 | http://purl.uniprot.org/core/title | "The origin and development of nonlymphoid tissue CD103+ DCs."xsd:string |
| http://purl.uniprot.org/citations/20008528 | http://purl.uniprot.org/core/volume | "206"xsd:string |
| http://purl.uniprot.org/citations/20008528 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/20008528 |
| http://purl.uniprot.org/citations/20008528 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/20008528 |
| http://purl.uniprot.org/uniprot/#_E0CZE4-mappedCitation-20008528 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20008528 |
| http://purl.uniprot.org/uniprot/#_A0A1B0GRC9-mappedCitation-20008528 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20008528 |