| http://purl.uniprot.org/citations/20010835 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/20010835 | http://www.w3.org/2000/01/rdf-schema#comment | "Spirometric measures of lung function are heritable traits that reflect respiratory health and predict morbidity and mortality. We meta-analyzed genome-wide association studies for two clinically important lung-function measures: forced expiratory volume in the first second (FEV(1)) and its ratio to forced vital capacity (FEV(1)/FVC), an indicator of airflow obstruction. This meta-analysis included 20,890 participants of European ancestry from four CHARGE Consortium studies: Atherosclerosis Risk in Communities, Cardiovascular Health Study, Framingham Heart Study and Rotterdam Study. We identified eight loci associated with FEV(1)/FVC (HHIP, GPR126, ADAM19, AGER-PPT2, FAM13A, PTCH1, PID1 and HTR4) and one locus associated with FEV(1) (INTS12-GSTCD-NPNT) at or near genome-wide significance (P < 5 x 10(-8)) in the CHARGE Consortium dataset. Our findings may offer insights into pulmonary function and pathogenesis of chronic lung disease."xsd:string |
| http://purl.uniprot.org/citations/20010835 | http://purl.org/dc/terms/identifier | "doi:10.1038/ng.500"xsd:string |
| http://purl.uniprot.org/citations/20010835 | http://purl.uniprot.org/core/author | "Franceschini N."xsd:string |
| http://purl.uniprot.org/citations/20010835 | http://purl.uniprot.org/core/author | "Rotter J.I."xsd:string |
| http://purl.uniprot.org/citations/20010835 | http://purl.uniprot.org/core/author | "Hofman A."xsd:string |
| http://purl.uniprot.org/citations/20010835 | http://purl.uniprot.org/core/author | "van Duijn C.M."xsd:string |
| http://purl.uniprot.org/citations/20010835 | http://purl.uniprot.org/core/author | "Rivadeneira F."xsd:string |
| http://purl.uniprot.org/citations/20010835 | http://purl.uniprot.org/core/author | "O'Connor G.T."xsd:string |
| http://purl.uniprot.org/citations/20010835 | http://purl.uniprot.org/core/author | "Uitterlinden A.G."xsd:string |
| http://purl.uniprot.org/citations/20010835 | http://purl.uniprot.org/core/author | "Psaty B.M."xsd:string |
| http://purl.uniprot.org/citations/20010835 | http://purl.uniprot.org/core/author | "London S.J."xsd:string |
| http://purl.uniprot.org/citations/20010835 | http://purl.uniprot.org/core/author | "Stricker B.H."xsd:string |
| http://purl.uniprot.org/citations/20010835 | http://purl.uniprot.org/core/author | "Lumley T."xsd:string |
| http://purl.uniprot.org/citations/20010835 | http://purl.uniprot.org/core/author | "North K.E."xsd:string |
| http://purl.uniprot.org/citations/20010835 | http://purl.uniprot.org/core/author | "Chen T.H."xsd:string |
| http://purl.uniprot.org/citations/20010835 | http://purl.uniprot.org/core/author | "Morrison A.C."xsd:string |
| http://purl.uniprot.org/citations/20010835 | http://purl.uniprot.org/core/author | "Barr R.G."xsd:string |
| http://purl.uniprot.org/citations/20010835 | http://purl.uniprot.org/core/author | "Brusselle G.G."xsd:string |
| http://purl.uniprot.org/citations/20010835 | http://purl.uniprot.org/core/author | "Gharib S.A."xsd:string |
| http://purl.uniprot.org/citations/20010835 | http://purl.uniprot.org/core/author | "Hancock D.B."xsd:string |
| http://purl.uniprot.org/citations/20010835 | http://purl.uniprot.org/core/author | "Heckbert S.R."xsd:string |
| http://purl.uniprot.org/citations/20010835 | http://purl.uniprot.org/core/author | "Loehr L.R."xsd:string |
| http://purl.uniprot.org/citations/20010835 | http://purl.uniprot.org/core/author | "Wilk J.B."xsd:string |
| http://purl.uniprot.org/citations/20010835 | http://purl.uniprot.org/core/author | "Eijgelsheim M."xsd:string |