http://purl.uniprot.org/citations/20026583 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/20026583 | http://www.w3.org/2000/01/rdf-schema#comment | "In Saccharomyces cerevisiae, TFIID and SAGA principally mediate transcription of constitutive housekeeping genes and stress-inducible genes, respectively, by delivering TBP to the core promoter. Both are multi-protein complexes composed of 15 and 20 subunits, respectively, five of which are common and which may constitute a core sub-module in each complex. Although genome-wide gene expression studies have been conducted extensively in several TFIID and/or SAGA mutants, there are only a limited number of studies investigating genome-wide localization of the components of these two complexes. Specifically, there are no previous reports on localization of a complete set of Tafs and the effects of taf mutations on localization. Here, we examine the localization profiles of a complete set of Tafs, Gcn5, Bur6/Ncb2, Sua7, Tfa2, Tfg1, Tfb3 and Rpb1, on chromosomes III, IV and V by chromatin immunoprecipitation (ChIP)-chip analysis in wild-type and taf1-T657K mutant strains. In addition, we conducted conventional and sequential ChIP analysis of several ribosomal protein genes (RPGs) and non-RPGs. Intriguingly, the results revealed a novel relationship between TFIIB and NC2, simultaneous co-localization of SAGA and TFIID on RPG promoters, specific effects of taf1 mutation on Taf2 occupancy, and an indirect evidence for the existence of different TFIID conformations."xsd:string |
http://purl.uniprot.org/citations/20026583 | http://purl.org/dc/terms/identifier | "doi:10.1093/nar/gkp1172"xsd:string |
http://purl.uniprot.org/citations/20026583 | http://purl.uniprot.org/core/author | "Shirahige K."xsd:string |
http://purl.uniprot.org/citations/20026583 | http://purl.uniprot.org/core/author | "Kokubo T."xsd:string |
http://purl.uniprot.org/citations/20026583 | http://purl.uniprot.org/core/author | "Kasahara K."xsd:string |
http://purl.uniprot.org/citations/20026583 | http://purl.uniprot.org/core/author | "Ohtsuki K."xsd:string |
http://purl.uniprot.org/citations/20026583 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
http://purl.uniprot.org/citations/20026583 | http://purl.uniprot.org/core/name | "Nucleic Acids Res"xsd:string |
http://purl.uniprot.org/citations/20026583 | http://purl.uniprot.org/core/pages | "1805-1820"xsd:string |
http://purl.uniprot.org/citations/20026583 | http://purl.uniprot.org/core/title | "Genome-wide localization analysis of a complete set of Tafs reveals a specific effect of the taf1 mutation on Taf2 occupancy and provides indirect evidence for different TFIID conformations at different promoters."xsd:string |
http://purl.uniprot.org/citations/20026583 | http://purl.uniprot.org/core/volume | "38"xsd:string |
http://purl.uniprot.org/citations/20026583 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/20026583 |
http://purl.uniprot.org/citations/20026583 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/20026583 |
http://purl.uniprot.org/uniprot/#_A0A8H4F669-mappedCitation-20026583 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20026583 |
http://purl.uniprot.org/uniprot/#_A0A8H8UL04-mappedCitation-20026583 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20026583 |
http://purl.uniprot.org/uniprot/#_P23255-mappedCitation-20026583 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20026583 |
http://purl.uniprot.org/uniprot/#_P46677-mappedCitation-20026583 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20026583 |
http://purl.uniprot.org/uniprot/#_P04050-mappedCitation-20026583 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20026583 |
http://purl.uniprot.org/uniprot/A0A8H8UL04 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/20026583 |
http://purl.uniprot.org/uniprot/P46677 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/20026583 |
http://purl.uniprot.org/uniprot/P04050 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/20026583 |
http://purl.uniprot.org/uniprot/P23255 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/20026583 |
http://purl.uniprot.org/uniprot/A0A8H4F669 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/20026583 |