http://purl.uniprot.org/citations/20037812 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/20037812 | http://www.w3.org/2000/01/rdf-schema#comment | "To investigate the effects of albumin on the production of matrix metalloproteinases-2 (MMP-2) and matrix metalloproteinases-9 (MMP-9) in podocytes. Podocytes were treated with bovine serum albumin (BSA) at the concentration of 0.1, 0.5, 1, 2 g/L, respectively. Conditioned media were harvested 12, 24, 48 and 72 h after the treatment. The expression of MMP-2 and MMP-9 was assayed by gelatin zymography, RT-PCR and Western blotting analysis. Our results showed that in comparison with the control group, BSA increased the expression of MMP-2 and MMP-9 mRNA and protein in a dose- and time-dependent manner (P<0.05). Meanwhile, the enzymatic activities of MMP-2 and MMP-9 in the culture supernatants of podocytes were also increased (P<0.05). It is concluded that albumin up-regulated the expression of MMP-2 and MMP-9 at gene and protein levels in a time- and dose-dependent manner."xsd:string |
http://purl.uniprot.org/citations/20037812 | http://purl.org/dc/terms/identifier | "doi:10.1007/s11596-009-0607-1"xsd:string |
http://purl.uniprot.org/citations/20037812 | http://purl.uniprot.org/core/author | "Chen S."xsd:string |
http://purl.uniprot.org/citations/20037812 | http://purl.uniprot.org/core/author | "He F."xsd:string |
http://purl.uniprot.org/citations/20037812 | http://purl.uniprot.org/core/author | "Fang Z."xsd:string |
http://purl.uniprot.org/citations/20037812 | http://purl.uniprot.org/core/author | "Sun X."xsd:string |
http://purl.uniprot.org/citations/20037812 | http://purl.uniprot.org/core/author | "Zhang C."xsd:string |
http://purl.uniprot.org/citations/20037812 | http://purl.uniprot.org/core/author | "Zhu Z."xsd:string |
http://purl.uniprot.org/citations/20037812 | http://purl.uniprot.org/core/date | "2009"xsd:gYear |
http://purl.uniprot.org/citations/20037812 | http://purl.uniprot.org/core/name | "J Huazhong Univ Sci Technolog Med Sci"xsd:string |
http://purl.uniprot.org/citations/20037812 | http://purl.uniprot.org/core/pages | "710-714"xsd:string |
http://purl.uniprot.org/citations/20037812 | http://purl.uniprot.org/core/title | "Albumin modulates the production of matrix metalloproteinases-2 and -9 in podocytes."xsd:string |
http://purl.uniprot.org/citations/20037812 | http://purl.uniprot.org/core/volume | "29"xsd:string |
http://purl.uniprot.org/citations/20037812 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/20037812 |
http://purl.uniprot.org/citations/20037812 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/20037812 |
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http://purl.uniprot.org/uniprot/#_Q2M4J5-mappedCitation-20037812 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20037812 |
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http://purl.uniprot.org/uniprot/#_Q6GXA2-mappedCitation-20037812 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20037812 |
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