| http://purl.uniprot.org/citations/20044538 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/20044538 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/20044538 | http://www.w3.org/2000/01/rdf-schema#comment | "Mammalian meiotic recombination, which preferentially occurs at specialized sites called hotspots, ensures the orderly segregation of meiotic chromosomes and creates genetic variation among offspring. A locus on mouse chromosome 17, which controls activation of recombination at multiple distant hotspots, has been mapped within a 181-kilobase interval, three of whose genes can be eliminated as candidates. The remaining gene, Prdm9, codes for a zinc finger containing histone H3K4 trimethylase that is expressed in early meiosis and whose deficiency results in sterility in both sexes. Mus musculus exhibits five alleles of Prdm9; human populations exhibit two predominant alleles and multiple minor alleles. The identification of Prdm9 as a protein regulating mammalian recombination hotspots initiates molecular studies of this important biological control system."xsd:string |
| http://purl.uniprot.org/citations/20044538 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1181495"xsd:string |
| http://purl.uniprot.org/citations/20044538 | http://purl.org/dc/terms/identifier | "doi:10.1126/science.1181495"xsd:string |
| http://purl.uniprot.org/citations/20044538 | http://purl.uniprot.org/core/author | "Paigen K."xsd:string |
| http://purl.uniprot.org/citations/20044538 | http://purl.uniprot.org/core/author | "Paigen K."xsd:string |
| http://purl.uniprot.org/citations/20044538 | http://purl.uniprot.org/core/author | "Parvanov E.D."xsd:string |
| http://purl.uniprot.org/citations/20044538 | http://purl.uniprot.org/core/author | "Parvanov E.D."xsd:string |
| http://purl.uniprot.org/citations/20044538 | http://purl.uniprot.org/core/author | "Petkov P.M."xsd:string |
| http://purl.uniprot.org/citations/20044538 | http://purl.uniprot.org/core/author | "Petkov P.M."xsd:string |
| http://purl.uniprot.org/citations/20044538 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
| http://purl.uniprot.org/citations/20044538 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
| http://purl.uniprot.org/citations/20044538 | http://purl.uniprot.org/core/name | "Science"xsd:string |
| http://purl.uniprot.org/citations/20044538 | http://purl.uniprot.org/core/name | "Science"xsd:string |
| http://purl.uniprot.org/citations/20044538 | http://purl.uniprot.org/core/pages | "835"xsd:string |
| http://purl.uniprot.org/citations/20044538 | http://purl.uniprot.org/core/pages | "835"xsd:string |
| http://purl.uniprot.org/citations/20044538 | http://purl.uniprot.org/core/title | "Prdm9 controls activation of mammalian recombination hotspots."xsd:string |
| http://purl.uniprot.org/citations/20044538 | http://purl.uniprot.org/core/title | "Prdm9 controls activation of mammalian recombination hotspots."xsd:string |
| http://purl.uniprot.org/citations/20044538 | http://purl.uniprot.org/core/volume | "327"xsd:string |
| http://purl.uniprot.org/citations/20044538 | http://purl.uniprot.org/core/volume | "327"xsd:string |
| http://purl.uniprot.org/citations/20044538 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/20044538 |
| http://purl.uniprot.org/citations/20044538 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/20044538 |
| http://purl.uniprot.org/citations/20044538 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/20044538 |
| http://purl.uniprot.org/citations/20044538 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/20044538 |