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http://purl.uniprot.org/citations/20059951http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/20059951http://www.w3.org/2000/01/rdf-schema#comment"The GTPase dynamin, a key player in endocytic membrane fission, interacts with numerous proteins that regulate actin dynamics and generate/sense membrane curvature. To determine the functional relationship between these proteins and dynamin, we have analyzed endocytic intermediates that accumulate in cells that lack dynamin (derived from dynamin 1 and 2 double conditional knockout mice). In these cells, actin-nucleating proteins, actin, and BAR domain proteins accumulate at the base of arrested endocytic clathrin-coated pits, where they support the growth of dynamic long tubular necks. These results, which we show reflect the sequence of events in wild-type cells, demonstrate a concerted action of these proteins prior to, and independent of, dynamin and emphasize similarities between clathrin-mediated endocytosis in yeast and higher eukaryotes. Our data also demonstrate that the relationship between dynamin and actin is intimately connected to dynamin's endocytic role and that dynamin terminates a powerful actin- and BAR protein-dependent tubulating activity."xsd:string
http://purl.uniprot.org/citations/20059951http://purl.org/dc/terms/identifier"doi:10.1016/j.devcel.2009.11.005"xsd:string
http://purl.uniprot.org/citations/20059951http://purl.uniprot.org/core/author"Shen H."xsd:string
http://purl.uniprot.org/citations/20059951http://purl.uniprot.org/core/author"Destaing O."xsd:string
http://purl.uniprot.org/citations/20059951http://purl.uniprot.org/core/author"Raimondi A."xsd:string
http://purl.uniprot.org/citations/20059951http://purl.uniprot.org/core/author"De Camilli P."xsd:string
http://purl.uniprot.org/citations/20059951http://purl.uniprot.org/core/author"Ferguson S.M."xsd:string
http://purl.uniprot.org/citations/20059951http://purl.uniprot.org/core/author"Cremona O."xsd:string
http://purl.uniprot.org/citations/20059951http://purl.uniprot.org/core/author"Ferguson S."xsd:string
http://purl.uniprot.org/citations/20059951http://purl.uniprot.org/core/author"Ferguson A."xsd:string
http://purl.uniprot.org/citations/20059951http://purl.uniprot.org/core/author"Takasaki J."xsd:string
http://purl.uniprot.org/citations/20059951http://purl.uniprot.org/core/author"Paradise S."xsd:string
http://purl.uniprot.org/citations/20059951http://purl.uniprot.org/core/author"Ko G."xsd:string
http://purl.uniprot.org/citations/20059951http://purl.uniprot.org/core/author"Mesaki K."xsd:string
http://purl.uniprot.org/citations/20059951http://purl.uniprot.org/core/author"O' Toole E."xsd:string
http://purl.uniprot.org/citations/20059951http://purl.uniprot.org/core/date"2009"xsd:gYear
http://purl.uniprot.org/citations/20059951http://purl.uniprot.org/core/name"Dev Cell"xsd:string
http://purl.uniprot.org/citations/20059951http://purl.uniprot.org/core/pages"811-822"xsd:string
http://purl.uniprot.org/citations/20059951http://purl.uniprot.org/core/title"Coordinated actions of actin and BAR proteins upstream of dynamin at endocytic clathrin-coated pits."xsd:string
http://purl.uniprot.org/citations/20059951http://purl.uniprot.org/core/volume"17"xsd:string
http://purl.uniprot.org/citations/20059951http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/20059951
http://purl.uniprot.org/citations/20059951http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/20059951
http://purl.uniprot.org/uniprot/#_A0A0J9YUE9-mappedCitation-20059951http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/20059951
http://purl.uniprot.org/uniprot/#_A0A0J9YUN4-mappedCitation-20059951http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/20059951