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http://purl.uniprot.org/citations/20059976http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/20059976http://www.w3.org/2000/01/rdf-schema#comment"Since the dentine is analogous to bone, its extracellular matrix shares many similarities to bone tissues. Similar to the bone, type I collagen is the major organic component in dentine. However, little is known about minor fibrillar collagens, which seem to be co-expressed such as type I or II collagen. The present study examined the gene expression of type V and XI collagens, which play important roles in collagen fibril formation and skeletal morphogenesis, using RT-PCR and in situ hybridization combined with immunohistochemistry. The transcripts of pro-alpha1(XI), pro-alpha2(XI), pro-alpha1(V) and pro-alpha2(V) chains were present, but not pro-alpha3(V) and pro-alpha1(II) chains, of which an overglycosylated variant is pro-alpha3(XI) chain, in mouse incisor tooth, using RT-PCR and in situ hybridization. The pro-alpha2(XI) protein, which is mainly expressed in cartilage, were observed in the odontoblast using a specific polyclonal antibody. Real-time RT-PCR showed that the transcripts of pro-alpha2(XI), pro-alpha1(V) and pro-alpha2(V) were predominant in crown and that of pro-alpha1(XI) in root of the tooth. Finally, the expression of pro-alpha2(XI) was confirmed with an odontoblastic cell line transformed with human telomerase reverse transcriptase (hTERT) both in vitro and in vivo. The data suggest a new subtype of the V/XI collagen molecule containing alpha2(XI) chain."xsd:string
http://purl.uniprot.org/citations/20059976http://purl.org/dc/terms/identifier"doi:10.1016/j.bbrc.2010.01.001"xsd:string
http://purl.uniprot.org/citations/20059976http://purl.uniprot.org/core/author"Nakashima M."xsd:string
http://purl.uniprot.org/citations/20059976http://purl.uniprot.org/core/author"Yoshioka H."xsd:string
http://purl.uniprot.org/citations/20059976http://purl.uniprot.org/core/author"Hamada Y."xsd:string
http://purl.uniprot.org/citations/20059976http://purl.uniprot.org/core/author"Matsuo N."xsd:string
http://purl.uniprot.org/citations/20059976http://purl.uniprot.org/core/author"Yanagisawa S."xsd:string
http://purl.uniprot.org/citations/20059976http://purl.uniprot.org/core/author"Sumiyoshi H."xsd:string
http://purl.uniprot.org/citations/20059976http://purl.uniprot.org/core/author"Yun-Feng W."xsd:string
http://purl.uniprot.org/citations/20059976http://purl.uniprot.org/core/date"2010"xsd:gYear
http://purl.uniprot.org/citations/20059976http://purl.uniprot.org/core/name"Biochem Biophys Res Commun"xsd:string
http://purl.uniprot.org/citations/20059976http://purl.uniprot.org/core/pages"166-170"xsd:string
http://purl.uniprot.org/citations/20059976http://purl.uniprot.org/core/title"The pro-alpha2(XI) collagen gene is expressed in odontoblasts."xsd:string
http://purl.uniprot.org/citations/20059976http://purl.uniprot.org/core/volume"392"xsd:string
http://purl.uniprot.org/citations/20059976http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/20059976
http://purl.uniprot.org/citations/20059976http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/20059976
http://purl.uniprot.org/uniprot/#_A0A068BD44-mappedCitation-20059976http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/20059976
http://purl.uniprot.org/uniprot/#_E9Q9Z9-mappedCitation-20059976http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/20059976
http://purl.uniprot.org/uniprot/#_A0A1D5RMJ0-mappedCitation-20059976http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/20059976
http://purl.uniprot.org/uniprot/#_P11087-mappedCitation-20059976http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/20059976
http://purl.uniprot.org/uniprot/#_A1L2Z1-mappedCitation-20059976http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/20059976
http://purl.uniprot.org/uniprot/#_A0A5F8MQ70-mappedCitation-20059976http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/20059976
http://purl.uniprot.org/uniprot/#_A1A4B3-mappedCitation-20059976http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/20059976
http://purl.uniprot.org/uniprot/#_A3KGE7-mappedCitation-20059976http://www.w3.org/1999/02/22-rdf-syntax-ns#objecthttp://purl.uniprot.org/citations/20059976