RDF/XMLNTriplesTurtleShow queryShare
SubjectPredicateObject
http://purl.uniprot.org/citations/20080406http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/20080406http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/20080406http://www.w3.org/2000/01/rdf-schema#comment"Eukaryotes employ a diversity of strategies to ensure that gametes come together, but the cellular climax is less varied: gamete plasma membranes must fuse to allow the combination of parental genomes. Recent studies of HAP2-GCS1, a sex-restricted transmembrane protein found in genomes representing all major eukaryotic taxa except fungi, suggest that a broad array of eukaryotic organisms could share a common mechanism for gamete fusion. Plant, protozoan, and algal gametes carrying loss-of-function mutations in HAP2-GCS1 fail to fuse with their complements. We propose that HAP2-GCS1 is a crucial component of an ancient mechanism that mediates the fusion of gamete plasma membranes and could have been a key early innovation in the evolution of sexual reproduction."xsd:string
http://purl.uniprot.org/citations/20080406http://purl.org/dc/terms/identifier"doi:10.1016/j.tcb.2009.12.007"xsd:string
http://purl.uniprot.org/citations/20080406http://purl.org/dc/terms/identifier"doi:10.1016/j.tcb.2009.12.007"xsd:string
http://purl.uniprot.org/citations/20080406http://purl.uniprot.org/core/author"Johnson M.A."xsd:string
http://purl.uniprot.org/citations/20080406http://purl.uniprot.org/core/author"Johnson M.A."xsd:string
http://purl.uniprot.org/citations/20080406http://purl.uniprot.org/core/author"Wong J.L."xsd:string
http://purl.uniprot.org/citations/20080406http://purl.uniprot.org/core/author"Wong J.L."xsd:string
http://purl.uniprot.org/citations/20080406http://purl.uniprot.org/core/date"2010"xsd:gYear
http://purl.uniprot.org/citations/20080406http://purl.uniprot.org/core/date"2010"xsd:gYear
http://purl.uniprot.org/citations/20080406http://purl.uniprot.org/core/name"Trends Cell Biol."xsd:string
http://purl.uniprot.org/citations/20080406http://purl.uniprot.org/core/name"Trends Cell Biol."xsd:string
http://purl.uniprot.org/citations/20080406http://purl.uniprot.org/core/pages"134-141"xsd:string
http://purl.uniprot.org/citations/20080406http://purl.uniprot.org/core/pages"134-141"xsd:string
http://purl.uniprot.org/citations/20080406http://purl.uniprot.org/core/title"Is HAP2-GCS1 an ancestral gamete fusogen?"xsd:string
http://purl.uniprot.org/citations/20080406http://purl.uniprot.org/core/title"Is HAP2-GCS1 an ancestral gamete fusogen?"xsd:string
http://purl.uniprot.org/citations/20080406http://purl.uniprot.org/core/volume"20"xsd:string
http://purl.uniprot.org/citations/20080406http://purl.uniprot.org/core/volume"20"xsd:string
http://purl.uniprot.org/citations/20080406http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/20080406
http://purl.uniprot.org/citations/20080406http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/20080406
http://purl.uniprot.org/citations/20080406http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/20080406
http://purl.uniprot.org/citations/20080406http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/20080406
http://purl.uniprot.org/uniprot/A4GRC6http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/20080406
http://purl.uniprot.org/uniprot/Q5W6B9http://purl.uniprot.org/core/citationhttp://purl.uniprot.org/citations/20080406