| http://purl.uniprot.org/citations/20084546 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/20084546 | http://www.w3.org/2000/01/rdf-schema#comment | "Published data on the association between insulin-like growth factor binding protein 3 (IGFBP3) A-202C polymorphism and breast cancer risk are inconclusive. To derive a more precise estimation of the relationship, a meta-analysis was performed. Crude ORs with 95% CIs were used to assess the strength of association between them. A total of 27 studies including 33,557 cases and 45,254 controls were involved in this meta-analysis. Overall, significantly elevated breast cancer risk was associated with IGFBP3 C allele when all studies were pooled into the meta-analysis (CC vs. AA: OR = 1.06, 95% CI = 1.02-1.11; dominant model: OR = 1.04, 95% CI = 1.00-1.07). In the subgroup analysis by ethnicity, significantly increased risk was found for Caucasians (AC vs. AA: OR = 1.04, 95% CI = 1.00-1.08; CC vs. AA: OR = 1.05, 95% CI = 1.01-1.10; dominant model: OR = 1.04, 95% CI = 1.00-1.08) and Asians (CC vs. AA: OR = 1.35, 95% CI = 1.02-1.78; recessive model: OR = 1.38, 95% CI = 1.05-1.82). When stratified by study design, statistically significantly elevated risk was found among population-based studies (CC vs. AA: OR = 1.06, 95% CI = 1.01-1.11; dominant model: OR = 1.03, 95% CI = 1.00-1.07). In the subgroup analysis by menopausal status, no statistically significantly increased risk was found among premenopausal or postmenopausal women. In conclusion, this meta-analysis suggests that the IGFBP3 C allele is a low-penetrant risk factor for developing breast cancer."xsd:string |
| http://purl.uniprot.org/citations/20084546 | http://purl.org/dc/terms/identifier | "doi:10.1007/s10549-010-0739-9"xsd:string |
| http://purl.uniprot.org/citations/20084546 | http://purl.uniprot.org/core/author | "Chen B."xsd:string |
| http://purl.uniprot.org/citations/20084546 | http://purl.uniprot.org/core/author | "Mao C."xsd:string |
| http://purl.uniprot.org/citations/20084546 | http://purl.uniprot.org/core/author | "Zhang J."xsd:string |
| http://purl.uniprot.org/citations/20084546 | http://purl.uniprot.org/core/author | "Hu X.C."xsd:string |
| http://purl.uniprot.org/citations/20084546 | http://purl.uniprot.org/core/author | "Yuan H."xsd:string |
| http://purl.uniprot.org/citations/20084546 | http://purl.uniprot.org/core/author | "Yao L."xsd:string |
| http://purl.uniprot.org/citations/20084546 | http://purl.uniprot.org/core/author | "Xue K."xsd:string |
| http://purl.uniprot.org/citations/20084546 | http://purl.uniprot.org/core/author | "Zhan P."xsd:string |
| http://purl.uniprot.org/citations/20084546 | http://purl.uniprot.org/core/author | "Qiu L.X."xsd:string |
| http://purl.uniprot.org/citations/20084546 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
| http://purl.uniprot.org/citations/20084546 | http://purl.uniprot.org/core/name | "Breast Cancer Res Treat"xsd:string |
| http://purl.uniprot.org/citations/20084546 | http://purl.uniprot.org/core/pages | "867-871"xsd:string |
| http://purl.uniprot.org/citations/20084546 | http://purl.uniprot.org/core/title | "IGFBP3 A-202C polymorphism and breast cancer susceptibility: a meta-analysis involving 33,557 cases and 45,254 controls."xsd:string |
| http://purl.uniprot.org/citations/20084546 | http://purl.uniprot.org/core/volume | "122"xsd:string |
| http://purl.uniprot.org/citations/20084546 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/20084546 |
| http://purl.uniprot.org/citations/20084546 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/20084546 |
| http://purl.uniprot.org/uniprot/#_B3KRZ1-mappedCitation-20084546 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20084546 |
| http://purl.uniprot.org/uniprot/#_B3KRJ8-mappedCitation-20084546 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20084546 |
| http://purl.uniprot.org/uniprot/#_B3KVF9-mappedCitation-20084546 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20084546 |
| http://purl.uniprot.org/uniprot/#_A6XNC9-mappedCitation-20084546 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20084546 |
| http://purl.uniprot.org/uniprot/#_A6XND0-mappedCitation-20084546 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20084546 |
| http://purl.uniprot.org/uniprot/#_A6XND1-mappedCitation-20084546 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20084546 |