http://purl.uniprot.org/citations/20117088 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
http://purl.uniprot.org/citations/20117088 | http://www.w3.org/2000/01/rdf-schema#comment | "DDA3 is a microtubule-associated protein that controls chromosome congression and segregation by regulating the mitotic spindle. Depletion of DDA3 alters spindle structure, generates unaligned chromosomes at metaphase, and delays the mitotic progression. Through a mass spectrometry analysis, we found that DDA3 is phosphorylated on Ser225 during mitosis. Phosphorylation of this residue is important for the mitotic function of DDA3, as the phospho-mimicking DDA3-S225D variant, but not the nonphosphorable DDA3-S225A mutant, rescues the DDA3-knockdown phenotype. We conclude that the mitotic function of DDA3 is regulated by phosphorylation on the Ser225 residue."xsd:string |
http://purl.uniprot.org/citations/20117088 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.bbrc.2010.01.115"xsd:string |
http://purl.uniprot.org/citations/20117088 | http://purl.uniprot.org/core/author | "Fang G."xsd:string |
http://purl.uniprot.org/citations/20117088 | http://purl.uniprot.org/core/author | "Yates J.R."xsd:string |
http://purl.uniprot.org/citations/20117088 | http://purl.uniprot.org/core/author | "Jang C.Y."xsd:string |
http://purl.uniprot.org/citations/20117088 | http://purl.uniprot.org/core/author | "Coppinger J.A."xsd:string |
http://purl.uniprot.org/citations/20117088 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
http://purl.uniprot.org/citations/20117088 | http://purl.uniprot.org/core/name | "Biochem Biophys Res Commun"xsd:string |
http://purl.uniprot.org/citations/20117088 | http://purl.uniprot.org/core/pages | "259-263"xsd:string |
http://purl.uniprot.org/citations/20117088 | http://purl.uniprot.org/core/title | "Phospho-regulation of DDA3 function in mitosis."xsd:string |
http://purl.uniprot.org/citations/20117088 | http://purl.uniprot.org/core/volume | "393"xsd:string |
http://purl.uniprot.org/citations/20117088 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/20117088 |
http://purl.uniprot.org/citations/20117088 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/20117088 |
http://purl.uniprot.org/uniprot/#_Q6PGN9-mappedCitation-20117088 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20117088 |
http://purl.uniprot.org/uniprot/Q6PGN9 | http://purl.uniprot.org/core/mappedCitation | http://purl.uniprot.org/citations/20117088 |