| http://purl.uniprot.org/citations/20123895 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/20123895 | http://www.w3.org/2000/01/rdf-schema#comment | "Trimethylation of histone H3 on Lys 27 (H3K27me3) is key for cell fate regulation. The H3K27me3 demethylase UTX functions in development and tumor suppression with undefined mechanisms. Here, genome-wide chromatin occupancy analysis of UTX and associated histone modifications reveals distinct classes of UTX target genes, including genes encoding Retinoblastoma (RB)-binding proteins. UTX removes H3K27me3 and maintains expression of several RB-binding proteins, enabling cell cycle arrest. Genetic interactions in mammalian cells and Caenorhabditis elegans show that UTX regulates cell fates via RB-dependent pathways. Thus, UTX defines an evolutionarily conserved mechanism to enable coordinate transcription of a RB network in cell fate control."xsd:string |
| http://purl.uniprot.org/citations/20123895 | http://purl.org/dc/terms/identifier | "doi:10.1101/gad.1882610"xsd:string |
| http://purl.uniprot.org/citations/20123895 | http://purl.uniprot.org/core/author | "Chen S."xsd:string |
| http://purl.uniprot.org/citations/20123895 | http://purl.uniprot.org/core/author | "Liu H."xsd:string |
| http://purl.uniprot.org/citations/20123895 | http://purl.uniprot.org/core/author | "Shi Y."xsd:string |
| http://purl.uniprot.org/citations/20123895 | http://purl.uniprot.org/core/author | "Chang H.Y."xsd:string |
| http://purl.uniprot.org/citations/20123895 | http://purl.uniprot.org/core/author | "Tsai M.C."xsd:string |
| http://purl.uniprot.org/citations/20123895 | http://purl.uniprot.org/core/author | "Adler A.S."xsd:string |
| http://purl.uniprot.org/citations/20123895 | http://purl.uniprot.org/core/author | "Wang J.K."xsd:string |
| http://purl.uniprot.org/citations/20123895 | http://purl.uniprot.org/core/author | "Poulin G."xsd:string |
| http://purl.uniprot.org/citations/20123895 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
| http://purl.uniprot.org/citations/20123895 | http://purl.uniprot.org/core/name | "Genes Dev"xsd:string |
| http://purl.uniprot.org/citations/20123895 | http://purl.uniprot.org/core/pages | "327-332"xsd:string |
| http://purl.uniprot.org/citations/20123895 | http://purl.uniprot.org/core/title | "The histone demethylase UTX enables RB-dependent cell fate control."xsd:string |
| http://purl.uniprot.org/citations/20123895 | http://purl.uniprot.org/core/volume | "24"xsd:string |
| http://purl.uniprot.org/citations/20123895 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/20123895 |
| http://purl.uniprot.org/citations/20123895 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/20123895 |
| http://purl.uniprot.org/uniprot/#_A0A131MBT2-mappedCitation-20123895 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20123895 |
| http://purl.uniprot.org/uniprot/#_A0A131MCP7-mappedCitation-20123895 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20123895 |
| http://purl.uniprot.org/uniprot/#_A0A087X0R0-mappedCitation-20123895 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20123895 |
| http://purl.uniprot.org/uniprot/#_B4DG81-mappedCitation-20123895 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20123895 |
| http://purl.uniprot.org/uniprot/#_A0A804HJA2-mappedCitation-20123895 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20123895 |
| http://purl.uniprot.org/uniprot/#_B4E253-mappedCitation-20123895 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20123895 |
| http://purl.uniprot.org/uniprot/#_B7ZKN1-mappedCitation-20123895 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20123895 |