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http://purl.uniprot.org/citations/2016300http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/2016300http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/2016300http://www.w3.org/2000/01/rdf-schema#comment"The protein toxin abrin, which possesses an N-glycosylase activity toward eukaryotic 28 S rRNA, may have a potential in the deliberate eradication of certain cells. Here we report, by polymerase chain reaction technique, the isolation of genomic DNA sequences encoding two distinct abrin A-chains. A third sequence which encoded a part of a third type of A-chain was also isolated. The deduced amino acid sequences of the two full-length A-chains were about 84% similar. Addition of mRNA encoding the full-length A-chains to reticulocyte lysate strongly inhibited protein synthesis in the lysates, and a corresponding glycosylase activity on rRNA was observed. Addition of the same mRNA to toxin-resistant wheat germ extracts led to synthesis of the expected 30-kDa protein which could be precipitated with antibodies specific for abrin."xsd:string
http://purl.uniprot.org/citations/2016300http://purl.org/dc/terms/identifier"doi:10.1016/s0021-9258(20)89578-7"xsd:string
http://purl.uniprot.org/citations/2016300http://purl.org/dc/terms/identifier"doi:10.1016/s0021-9258(20)89578-7"xsd:string
http://purl.uniprot.org/citations/2016300http://purl.uniprot.org/core/author"Evensen G."xsd:string
http://purl.uniprot.org/citations/2016300http://purl.uniprot.org/core/author"Evensen G."xsd:string
http://purl.uniprot.org/citations/2016300http://purl.uniprot.org/core/author"Mathiesen A."xsd:string
http://purl.uniprot.org/citations/2016300http://purl.uniprot.org/core/author"Mathiesen A."xsd:string
http://purl.uniprot.org/citations/2016300http://purl.uniprot.org/core/author"Sundan A."xsd:string
http://purl.uniprot.org/citations/2016300http://purl.uniprot.org/core/author"Sundan A."xsd:string
http://purl.uniprot.org/citations/2016300http://purl.uniprot.org/core/date"1991"xsd:gYear
http://purl.uniprot.org/citations/2016300http://purl.uniprot.org/core/date"1991"xsd:gYear
http://purl.uniprot.org/citations/2016300http://purl.uniprot.org/core/name"J. Biol. Chem."xsd:string
http://purl.uniprot.org/citations/2016300http://purl.uniprot.org/core/name"J. Biol. Chem."xsd:string
http://purl.uniprot.org/citations/2016300http://purl.uniprot.org/core/pages"6848-6852"xsd:string
http://purl.uniprot.org/citations/2016300http://purl.uniprot.org/core/pages"6848-6852"xsd:string
http://purl.uniprot.org/citations/2016300http://purl.uniprot.org/core/title"Direct molecular cloning and expression of two distinct abrin A-chains."xsd:string
http://purl.uniprot.org/citations/2016300http://purl.uniprot.org/core/title"Direct molecular cloning and expression of two distinct abrin A-chains."xsd:string
http://purl.uniprot.org/citations/2016300http://purl.uniprot.org/core/volume"266"xsd:string
http://purl.uniprot.org/citations/2016300http://purl.uniprot.org/core/volume"266"xsd:string
http://purl.uniprot.org/citations/2016300http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/2016300
http://purl.uniprot.org/citations/2016300http://www.w3.org/2004/02/skos/core#exactMatchhttp://purl.uniprot.org/pubmed/2016300
http://purl.uniprot.org/citations/2016300http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/2016300
http://purl.uniprot.org/citations/2016300http://xmlns.com/foaf/0.1/primaryTopicOfhttps://pubmed.ncbi.nlm.nih.gov/2016300