| http://purl.uniprot.org/citations/20173330 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/20173330 | http://www.w3.org/2000/01/rdf-schema#comment | "Increasing evidence supports a putative link between LRRK2 function and the MAP kinase cascades. We recently demonstrated that LRRK2 binds to MKK6, -3, and -7. Previous studies demonstrated that scaffold proteins are essential in the regulation of subcellular localization of stress kinase complexes. The c-jun NH2-terminal kinase (JNK)-interacting proteins (JIPs) are a group of scaffold proteins that play an important role in the regulation of MAP kinase signaling cascades. JIP1-3 are known to regulate the specificity and localization of the JNK pathway, while JIP4 is a specific scaffolding protein for the p38 pathway. We demonstrate that LRRK2 binds to JIP1-4, and is associated with increased levels of total JIP1, -3, -4, oligomeric JIP and ubiquitinated JIP. These results are consistent with a putative role of LRRK2 in regulating the stress kinase cascade."xsd:string |
| http://purl.uniprot.org/citations/20173330 | http://purl.org/dc/terms/identifier | "doi:10.1159/000285509"xsd:string |
| http://purl.uniprot.org/citations/20173330 | http://purl.uniprot.org/core/author | "Hsu C.H."xsd:string |
| http://purl.uniprot.org/citations/20173330 | http://purl.uniprot.org/core/author | "Chan D."xsd:string |
| http://purl.uniprot.org/citations/20173330 | http://purl.uniprot.org/core/author | "Wolozin B."xsd:string |
| http://purl.uniprot.org/citations/20173330 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
| http://purl.uniprot.org/citations/20173330 | http://purl.uniprot.org/core/name | "Neurodegener Dis"xsd:string |
| http://purl.uniprot.org/citations/20173330 | http://purl.uniprot.org/core/pages | "68-75"xsd:string |
| http://purl.uniprot.org/citations/20173330 | http://purl.uniprot.org/core/title | "LRRK2 and the stress response: interaction with MKKs and JNK-interacting proteins."xsd:string |
| http://purl.uniprot.org/citations/20173330 | http://purl.uniprot.org/core/volume | "7"xsd:string |
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