| http://purl.uniprot.org/citations/20176020 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/20176020 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/20176020 | http://www.w3.org/2000/01/rdf-schema#comment | "Malonyl-CoA-acyl carrier protein transacylase (MCAT) transfers the malonyl group from malonyl-CoA to holo-acyl carrier protein (ACP), and since malonyl-ACP is a key building block for fatty-acid biosynthesis it is considered as a promising antibacterial target. The crystal structures of MCAT from Staphylococcus aureus and Streptococcus pneumoniae have been determined at 1.46 and 2.1A resolution, respectively. In the SaMCAT structure, the N-terminal expression peptide of a neighboring molecule running in the opposite direction of malonyl-CoA makes extensive interactions with the highly conserved "Gly-Gln-Gly-Ser-Gln" stretch, suggesting a new design platform. Mutagenesis results suggest that Ser91 and His199 are the catalytic dyad."xsd:string |
| http://purl.uniprot.org/citations/20176020 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2010.02.038"xsd:string |
| http://purl.uniprot.org/citations/20176020 | http://purl.org/dc/terms/identifier | "doi:10.1016/j.febslet.2010.02.038"xsd:string |
| http://purl.uniprot.org/citations/20176020 | http://purl.uniprot.org/core/author | "Kim Y."xsd:string |
| http://purl.uniprot.org/citations/20176020 | http://purl.uniprot.org/core/author | "Kim Y."xsd:string |
| http://purl.uniprot.org/citations/20176020 | http://purl.uniprot.org/core/author | "Hong S.K."xsd:string |
| http://purl.uniprot.org/citations/20176020 | http://purl.uniprot.org/core/author | "Hong S.K."xsd:string |
| http://purl.uniprot.org/citations/20176020 | http://purl.uniprot.org/core/author | "Kim K.H."xsd:string |
| http://purl.uniprot.org/citations/20176020 | http://purl.uniprot.org/core/author | "Kim K.H."xsd:string |
| http://purl.uniprot.org/citations/20176020 | http://purl.uniprot.org/core/author | "Park J.K."xsd:string |
| http://purl.uniprot.org/citations/20176020 | http://purl.uniprot.org/core/author | "Park J.K."xsd:string |
| http://purl.uniprot.org/citations/20176020 | http://purl.uniprot.org/core/author | "Kim E.E."xsd:string |
| http://purl.uniprot.org/citations/20176020 | http://purl.uniprot.org/core/author | "Kim E.E."xsd:string |
| http://purl.uniprot.org/citations/20176020 | http://purl.uniprot.org/core/author | "Jeong K.W."xsd:string |
| http://purl.uniprot.org/citations/20176020 | http://purl.uniprot.org/core/author | "Jeong K.W."xsd:string |
| http://purl.uniprot.org/citations/20176020 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
| http://purl.uniprot.org/citations/20176020 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
| http://purl.uniprot.org/citations/20176020 | http://purl.uniprot.org/core/name | "FEBS Lett."xsd:string |
| http://purl.uniprot.org/citations/20176020 | http://purl.uniprot.org/core/name | "FEBS Lett"xsd:string |
| http://purl.uniprot.org/citations/20176020 | http://purl.uniprot.org/core/pages | "1240-1244"xsd:string |
| http://purl.uniprot.org/citations/20176020 | http://purl.uniprot.org/core/pages | "1240-1244"xsd:string |
| http://purl.uniprot.org/citations/20176020 | http://purl.uniprot.org/core/title | "New design platform for malonyl-CoA-acyl carrier protein transacylase."xsd:string |
| http://purl.uniprot.org/citations/20176020 | http://purl.uniprot.org/core/title | "New design platform for malonyl-CoA-acyl carrier protein transacylase."xsd:string |