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http://purl.uniprot.org/citations/20185686http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/20185686http://www.w3.org/1999/02/22-rdf-syntax-ns#typehttp://purl.uniprot.org/core/Journal_Citation
http://purl.uniprot.org/citations/20185686http://www.w3.org/2000/01/rdf-schema#comment"CKAMP44, identified here by a proteomic approach, is a brain-specific type I transmembrane protein that associates with AMPA receptors in synaptic spines. CKAMP44 expressed in Xenopus oocytes reduced GluA1- and A2-mediated steady-state currents, but did not affect kainate- or N-methyl-D-aspartate (NMDA) receptor-mediated currents. Mouse hippocampal CA1 pyramidal neurons expressed CKAMP44 at low abundance, and overexpression of CKAMP44 led to stronger and faster AMPA receptor desensitization, slower recovery from desensitization, and a reduction in the paired-pulse ratio of AMPA currents. By contrast, dentate gyrus granule cells exhibited strong CKAMP44 expression, and CKAMP44 knockout increased the paired-pulse ratio of AMPA currents in lateral and medial perforant path-granule cell synapses. CKAMP44 thus modulates short-term plasticity at specific excitatory synapses."xsd:string
http://purl.uniprot.org/citations/20185686http://purl.org/dc/terms/identifier"doi:10.1126/science.1184178"xsd:string
http://purl.uniprot.org/citations/20185686http://purl.org/dc/terms/identifier"doi:10.1126/science.1184178"xsd:string
http://purl.uniprot.org/citations/20185686http://purl.uniprot.org/core/author"Li K.W."xsd:string
http://purl.uniprot.org/citations/20185686http://purl.uniprot.org/core/author"Li K.W."xsd:string
http://purl.uniprot.org/citations/20185686http://purl.uniprot.org/core/author"Sprengel R."xsd:string
http://purl.uniprot.org/citations/20185686http://purl.uniprot.org/core/author"Sprengel R."xsd:string
http://purl.uniprot.org/citations/20185686http://purl.uniprot.org/core/author"Smit A.B."xsd:string
http://purl.uniprot.org/citations/20185686http://purl.uniprot.org/core/author"Smit A.B."xsd:string
http://purl.uniprot.org/citations/20185686http://purl.uniprot.org/core/author"Seeburg P.H."xsd:string
http://purl.uniprot.org/citations/20185686http://purl.uniprot.org/core/author"Seeburg P.H."xsd:string
http://purl.uniprot.org/citations/20185686http://purl.uniprot.org/core/author"Monyer H."xsd:string
http://purl.uniprot.org/citations/20185686http://purl.uniprot.org/core/author"Monyer H."xsd:string
http://purl.uniprot.org/citations/20185686http://purl.uniprot.org/core/author"Mack V."xsd:string
http://purl.uniprot.org/citations/20185686http://purl.uniprot.org/core/author"Mack V."xsd:string
http://purl.uniprot.org/citations/20185686http://purl.uniprot.org/core/author"Stern-Bach Y."xsd:string
http://purl.uniprot.org/citations/20185686http://purl.uniprot.org/core/author"Stern-Bach Y."xsd:string
http://purl.uniprot.org/citations/20185686http://purl.uniprot.org/core/author"Kavenstock N."xsd:string
http://purl.uniprot.org/citations/20185686http://purl.uniprot.org/core/author"Kavenstock N."xsd:string
http://purl.uniprot.org/citations/20185686http://purl.uniprot.org/core/author"von Engelhardt J."xsd:string
http://purl.uniprot.org/citations/20185686http://purl.uniprot.org/core/author"von Engelhardt J."xsd:string
http://purl.uniprot.org/citations/20185686http://purl.uniprot.org/core/date"2010"xsd:gYear
http://purl.uniprot.org/citations/20185686http://purl.uniprot.org/core/date"2010"xsd:gYear