| http://purl.uniprot.org/citations/20190758 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/20190758 | http://www.w3.org/2000/01/rdf-schema#comment | "Cross-priming allows dendritic cells (DCs) to induce cytotoxic T cell (CTL) responses to extracellular antigens. DCs require cognate 'licensing' for cross-priming, classically by helper T cells. Here we demonstrate an alternative mechanism for cognate licensing by natural killer T (NKT) cells recognizing microbial or synthetic glycolipid antigens. Such licensing caused cross-priming CD8alpha(+) DCs to produce the chemokine CCL17, which attracted naive CTLs expressing the chemokine receptor CCR4. In contrast, DCs licensed by helper T cells recruited CTLs using CCR5 ligands. Thus, depending on the type of antigen they encounter, DCs can be licensed for cross-priming by NKT cells or helper T cells and use at least two independent chemokine pathways to attract naive CTLs. Because these chemokines acted synergistically, this can potentially be exploited to improve vaccinations."xsd:string |
| http://purl.uniprot.org/citations/20190758 | http://purl.org/dc/terms/identifier | "doi:10.1038/ni.1848"xsd:string |
| http://purl.uniprot.org/citations/20190758 | http://purl.uniprot.org/core/author | "Cao J."xsd:string |
| http://purl.uniprot.org/citations/20190758 | http://purl.uniprot.org/core/author | "Rossjohn J."xsd:string |
| http://purl.uniprot.org/citations/20190758 | http://purl.uniprot.org/core/author | "Godfrey D.I."xsd:string |
| http://purl.uniprot.org/citations/20190758 | http://purl.uniprot.org/core/author | "Savage P.B."xsd:string |
| http://purl.uniprot.org/citations/20190758 | http://purl.uniprot.org/core/author | "Knolle P.A."xsd:string |
| http://purl.uniprot.org/citations/20190758 | http://purl.uniprot.org/core/author | "Kolanus W."xsd:string |
| http://purl.uniprot.org/citations/20190758 | http://purl.uniprot.org/core/author | "Forster I."xsd:string |
| http://purl.uniprot.org/citations/20190758 | http://purl.uniprot.org/core/author | "Thaiss C.A."xsd:string |
| http://purl.uniprot.org/citations/20190758 | http://purl.uniprot.org/core/author | "Panzer U."xsd:string |
| http://purl.uniprot.org/citations/20190758 | http://purl.uniprot.org/core/author | "Kurts C."xsd:string |
| http://purl.uniprot.org/citations/20190758 | http://purl.uniprot.org/core/author | "Quast T."xsd:string |
| http://purl.uniprot.org/citations/20190758 | http://purl.uniprot.org/core/author | "Perlmutter P."xsd:string |
| http://purl.uniprot.org/citations/20190758 | http://purl.uniprot.org/core/author | "Lukacs-Kornek V."xsd:string |
| http://purl.uniprot.org/citations/20190758 | http://purl.uniprot.org/core/author | "Hochheiser K."xsd:string |
| http://purl.uniprot.org/citations/20190758 | http://purl.uniprot.org/core/author | "Semmling V."xsd:string |
| http://purl.uniprot.org/citations/20190758 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
| http://purl.uniprot.org/citations/20190758 | http://purl.uniprot.org/core/name | "Nat Immunol"xsd:string |
| http://purl.uniprot.org/citations/20190758 | http://purl.uniprot.org/core/pages | "313-320"xsd:string |
| http://purl.uniprot.org/citations/20190758 | http://purl.uniprot.org/core/title | "Alternative cross-priming through CCL17-CCR4-mediated attraction of CTLs toward NKT cell-licensed DCs."xsd:string |
| http://purl.uniprot.org/citations/20190758 | http://purl.uniprot.org/core/volume | "11"xsd:string |
| http://purl.uniprot.org/citations/20190758 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/20190758 |
| http://purl.uniprot.org/citations/20190758 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/20190758 |