| http://purl.uniprot.org/citations/20200945 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/20200945 | http://www.w3.org/2000/01/rdf-schema#comment | "Axial growth of long bones occurs through a coordinated process of growth plate chondrocyte proliferation and differentiation. This maturation of chondrocytes is reflected in a zonal change in gene expression and cell morphology from resting to proliferative, prehypertrophic, and hypertrophic chondrocytes of the growth plate followed by ossification. A major experimental limitation in understanding growth plate biology and pathophysiology is the lack of a robust technique to isolate cells from the different zones, particularly from small animals. Here, we report on a new strategy for separating distinct chondrocyte populations from mouse growth plates. By transcriptome profiling of microdissected zones of growth plates, we identified novel, zone-specific cell surface markers and used these for flow cytometry and immunomagnetic cell separation to quantify, enrich, and characterize chondrocytes populations with respect to their differentiation status. This approach provides a novel platform to study cartilage development and characterize mouse growth plate chondrocytes to reveal unique cellular phenotypes of the distinct subpopulations within the growth plate."xsd:string |
| http://purl.uniprot.org/citations/20200945 | http://purl.org/dc/terms/identifier | "doi:10.1002/jbmr.30"xsd:string |
| http://purl.uniprot.org/citations/20200945 | http://purl.uniprot.org/core/author | "Brachvogel B."xsd:string |
| http://purl.uniprot.org/citations/20200945 | http://purl.uniprot.org/core/author | "von der Mark K."xsd:string |
| http://purl.uniprot.org/citations/20200945 | http://purl.uniprot.org/core/author | "Vogel S."xsd:string |
| http://purl.uniprot.org/citations/20200945 | http://purl.uniprot.org/core/author | "Bateman J.F."xsd:string |
| http://purl.uniprot.org/citations/20200945 | http://purl.uniprot.org/core/author | "Belluoccio D."xsd:string |
| http://purl.uniprot.org/citations/20200945 | http://purl.uniprot.org/core/author | "Etich J."xsd:string |
| http://purl.uniprot.org/citations/20200945 | http://purl.uniprot.org/core/author | "Zaucke F."xsd:string |
| http://purl.uniprot.org/citations/20200945 | http://purl.uniprot.org/core/author | "Frie C."xsd:string |
| http://purl.uniprot.org/citations/20200945 | http://purl.uniprot.org/core/author | "Rosenbaum S."xsd:string |
| http://purl.uniprot.org/citations/20200945 | http://purl.uniprot.org/core/author | "Grskovic I."xsd:string |
| http://purl.uniprot.org/citations/20200945 | http://purl.uniprot.org/core/author | "Ehlen H."xsd:string |
| http://purl.uniprot.org/citations/20200945 | http://purl.uniprot.org/core/author | "Stermann J."xsd:string |
| http://purl.uniprot.org/citations/20200945 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
| http://purl.uniprot.org/citations/20200945 | http://purl.uniprot.org/core/name | "J Bone Miner Res"xsd:string |
| http://purl.uniprot.org/citations/20200945 | http://purl.uniprot.org/core/pages | "1267-1281"xsd:string |
| http://purl.uniprot.org/citations/20200945 | http://purl.uniprot.org/core/title | "Sorting of growth plate chondrocytes allows the isolation and characterization of cells of a defined differentiation status."xsd:string |
| http://purl.uniprot.org/citations/20200945 | http://purl.uniprot.org/core/volume | "25"xsd:string |
| http://purl.uniprot.org/citations/20200945 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/20200945 |
| http://purl.uniprot.org/citations/20200945 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/20200945 |
| http://purl.uniprot.org/uniprot/#_D3Z7U5-mappedCitation-20200945 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20200945 |
| http://purl.uniprot.org/uniprot/#_A0A0J9YTQ5-mappedCitation-20200945 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20200945 |
| http://purl.uniprot.org/uniprot/#_A0A0J9YU04-mappedCitation-20200945 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20200945 |