| http://purl.uniprot.org/citations/20207982 | http://www.w3.org/1999/02/22-rdf-syntax-ns#type | http://purl.uniprot.org/core/Journal_Citation |
| http://purl.uniprot.org/citations/20207982 | http://www.w3.org/2000/01/rdf-schema#comment | "Posttransplantation non-Hodgkin lymphoma is a life-threatening complication after transplantation. Although pharmacologically suppressed adaptive immunity plays a major role in its development, the role of innate immunity in posttransplantation lymphoma is unknown. We assessed the 158 V/F polymorphism in the Fc-gamma receptor 3A gene (FCGR3A), killer cell immunoglobulin-like receptor (KIR) genotype, KIR ligand status, and a single nucleotide polymorphism affecting the production of interferon-gamma (IFN-gamma; +874 A/T) in 236 patients with posttransplantation lymphoma reported to the Collaborative Transplant Study. In addition, polymorphisms in the interleukin-10 (IL-10) and transforming growth factor-beta (TGF-beta) genes previously associated with lymphoma development were also typed. Using a split-cohort approach, gene/allele frequency was related to the 5-year patient survival after the diagnosis of lymphoma and compared with 100 control solid organ transplant recipients. FCGR3A and KIR genotype significantly influenced survival after diagnosis of posttransplantation lymphoma: the hazard of dying was reduced in homozygous carriers of the high-affinity V allele (hazard ratio 0.49, 95% confidence interval 0.29-0.82, P = .006), whereas carrying a genotype including KIR2DL2/KIR2DS2 increased the risk of dying (hazard ratio 1.49, 95% confidence interval 1.07-2.05, P = .02). KIR ligands and cytokine polymorphisms had no effect on survival. None of the genetic loci analyzed emerged as risk factors for lymphoma development."xsd:string |
| http://purl.uniprot.org/citations/20207982 | http://purl.org/dc/terms/identifier | "doi:10.1182/blood-2009-10-250134"xsd:string |
| http://purl.uniprot.org/citations/20207982 | http://purl.uniprot.org/core/author | "Stern M."xsd:string |
| http://purl.uniprot.org/citations/20207982 | http://purl.uniprot.org/core/author | "Opelz G."xsd:string |
| http://purl.uniprot.org/citations/20207982 | http://purl.uniprot.org/core/author | "Hess C."xsd:string |
| http://purl.uniprot.org/citations/20207982 | http://purl.uniprot.org/core/author | "Dohler B."xsd:string |
| http://purl.uniprot.org/citations/20207982 | http://purl.uniprot.org/core/date | "2010"xsd:gYear |
| http://purl.uniprot.org/citations/20207982 | http://purl.uniprot.org/core/name | "Blood"xsd:string |
| http://purl.uniprot.org/citations/20207982 | http://purl.uniprot.org/core/pages | "3960-3965"xsd:string |
| http://purl.uniprot.org/citations/20207982 | http://purl.uniprot.org/core/title | "Natural killer-cell receptor polymorphisms and posttransplantation non-Hodgkin lymphoma."xsd:string |
| http://purl.uniprot.org/citations/20207982 | http://purl.uniprot.org/core/volume | "115"xsd:string |
| http://purl.uniprot.org/citations/20207982 | http://www.w3.org/2004/02/skos/core#exactMatch | http://purl.uniprot.org/pubmed/20207982 |
| http://purl.uniprot.org/citations/20207982 | http://xmlns.com/foaf/0.1/primaryTopicOf | https://pubmed.ncbi.nlm.nih.gov/20207982 |
| http://purl.uniprot.org/uniprot/#_A0A0C4ZLQ8-mappedCitation-20207982 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20207982 |
| http://purl.uniprot.org/uniprot/#_A0A0C4ZN05-mappedCitation-20207982 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20207982 |
| http://purl.uniprot.org/uniprot/#_A0A0C4ZN11-mappedCitation-20207982 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20207982 |
| http://purl.uniprot.org/uniprot/#_A0A0C4ZN23-mappedCitation-20207982 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20207982 |
| http://purl.uniprot.org/uniprot/#_A0A0C4ZN30-mappedCitation-20207982 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20207982 |
| http://purl.uniprot.org/uniprot/#_A0A0C4ZN31-mappedCitation-20207982 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20207982 |
| http://purl.uniprot.org/uniprot/#_A0A0C4ZNX3-mappedCitation-20207982 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20207982 |
| http://purl.uniprot.org/uniprot/#_A0A0G2JLQ3-mappedCitation-20207982 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20207982 |
| http://purl.uniprot.org/uniprot/#_A0A0G2JLX2-mappedCitation-20207982 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20207982 |
| http://purl.uniprot.org/uniprot/#_A0A078BBI5-mappedCitation-20207982 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20207982 |
| http://purl.uniprot.org/uniprot/#_A0A078BC11-mappedCitation-20207982 | http://www.w3.org/1999/02/22-rdf-syntax-ns#object | http://purl.uniprot.org/citations/20207982 |